Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial
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|ClinicalTrials.gov Identifier: NCT00520338|
Recruitment Status : Completed
First Posted : August 24, 2007
Last Update Posted : November 9, 2010
The purpose of this study is to determine whether celecoxib is effective in the treatment postoperative pain after thyroidectomy.
The research hypothesis:
There is a difference in postoperative morphine consumption in the first 24 hours after thyroidectomy between patients who received celecoxib or placebo.
|Condition or disease||Intervention/treatment||Phase|
|Postoperative Pain Thyroidectomy Cyclooxygenase 2 Inhibitors||Drug: celecoxib||Phase 4|
Postoperative pain has been concerned in the past few years by both the anesthesiologists ans the surgeons. COX2-inhibitors have played an important roles in postoperative pain with minimal side effects.
Comparison(s): There is a difference in postoperative morphine consumption in the first 24 hours after thyroidectomy between patients who received celecoxib and placebo.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||80 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial|
|Study Start Date :||August 2007|
|Actual Primary Completion Date :||December 2009|
|Actual Study Completion Date :||December 2009|
Placebo Comparator: 2
Other Name: celebrex
No Intervention: 1
- The patients' total amount of morphine requirement in the first 24 hour. [ Time Frame: 24 hour ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00520338
|Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University|
|Bangkok, Thailand, 10700|
|Principal Investigator:||Sirilak Suksompong, MD||Department of anesthesiology. Siriraj Hospital, Mahidol University, Bangkok, Thailand|