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Trial record 14 of 482 for:    colon cancer | ( Map: Texas, United States )

Screening for Gynecologic Cancers in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00508846
Recruitment Status : Completed
First Posted : July 30, 2007
Last Update Posted : March 11, 2016
Information provided by (Responsible Party):
M.D. Anderson Cancer Center

Brief Summary:

Among women with HNPCC, this study will assess:

  1. Knowledge of screening recommendations for endometrial and ovarian cancers.
  2. Perceived risk and cancer worries regarding endometrial, ovarian and colorectal cancers.
  3. Adherence to screening recommendations for endometrial, ovarian and colon cancers.
  4. Perceived benefits,supports and barriers to endometrial and ovarian cancer screening.
  5. Patterns of communication about endometrial and ovarian cancer risk within families with HNPCC and with health care providers.
  6. Patient preferences for potential cancer screening and cancer prevention strategies related to HNPCC-associated cancers.

Condition or disease Intervention/treatment
Colon Cancer Behavioral: Questionnaire

Detailed Description:

Women who are at risk for HNPCC will be recruited to participate in this pilot study.

Women will be invited to participate in the study either through a mailed invitation or during a visit to M.D. Anderson for clinical services or for research purposes.

Women who wish to participate in the study will complete an informed consent, and will subsequently schedule an appointment with a research coordinator to complete the study questionnaire by telephone.

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Study Type : Observational
Actual Enrollment : 93 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Screening for Gynecologic Cancers Among Women With Hereditary Non-Polyposis Colon Cancer (HNPCC)
Study Start Date : May 2003
Actual Primary Completion Date : March 2016
Actual Study Completion Date : March 2016

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
HNPCC Patients Behavioral: Questionnaire
Two-part telephone questionnaire lasting about 60 minutes total.
Other Name: Survey

Primary Outcome Measures :
  1. Patient Responses to Questionnaire [ Time Frame: 7 Years ]
    Outcomes measuring demographics, surveillance behaviors, perceived risk, and cancer worries, screening supports/benefits and barriers.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   25 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Women, age 25 years of age or older, diagnosed with Hereditary Non-Polyposis Colon Cancer (HNPCC).

Inclusion Criteria:

  1. Being female
  2. Being 25 years of age or older
  3. Having an HNPCC-predisposing mutation and/or having a family history of cancer that meets the Amsterdam or Amsterdam II criteria for HNPCC

Exclusion Criteria:

  1. Persons who have tested negative for a known HNPCC-predisposing mutation in their family
  2. Persons who have no family HNPCC mutation and have not met the Amsterdam I/II criteria
  3. Being younger than 25 years old
  4. Note: Women who have had a prior history of colorectal cancer or polyps will not be excluded unless they meet one of the above exclusion criteria.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00508846

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United States, Texas
University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030
Sponsors and Collaborators
M.D. Anderson Cancer Center
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Principal Investigator: Susan Peterson, PhD M.D. Anderson Cancer Center

Additional Information:
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Responsible Party: M.D. Anderson Cancer Center Identifier: NCT00508846     History of Changes
Other Study ID Numbers: ID03-0211
First Posted: July 30, 2007    Key Record Dates
Last Update Posted: March 11, 2016
Last Verified: March 2016
Keywords provided by M.D. Anderson Cancer Center:
Hereditary Non-Polyposis Colon Cancer
Gynecologic Cancers
Genetic Counseling
Additional relevant MeSH terms:
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Colonic Neoplasms
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Colonic Diseases
Digestive System Diseases
Gastrointestinal Diseases
Intestinal Diseases