Prospective Study of Dietary Factors, BMI, and Risk of Asthma in Children
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00454415|
Recruitment Status : Completed
First Posted : March 30, 2007
Last Update Posted : December 27, 2012
|Condition or disease|
Asthma prevalence has steadily increased in the United States since the early 1980s, but the exact cause of this increase remains unknown. It is estimated that at least 8% of Americans have asthma. Although anti-inflammatory medications have proven effective for decreasing asthma exacerbations, there are few treatment options available to prevent the initial onset of the disease. Dietary factors and BMI may play a role in the development of asthma. Specifically, individuals who eat foods containing antioxidants (e.g., vitamin C, vitamin E, and carotenoids), n-3 polyunsaturated fatty acids (e.g., fish oils), and vitamin D may have a decreased risk of developing asthma, while individuals with higher BMI ratios may have an increased asthma risk. The purpose of this study is to evaluate the relationship among dietary factors, BMI, and the incidence of asthma among children.
This study will enroll children participating in the Growing Up Today study and children of nurses who are participating in the Nurses Health Study II. Researchers will analyze participants' previously completed questionnaires on dietary intake, physical activity, height, weight, and the presence of physician-diagnosed asthma. All participants with physician-diagnosed asthma will receive an additional asthma questionnaire. A small portion of these participants will also have their medical records reviewed by study researchers, and mothers of these children will be asked to complete a questionnaire. Additionally, a questionnaire will be sent to and completed by children who do not have asthma and their mothers.
|Study Type :||Observational|
|Actual Enrollment :||16000 participants|
|Official Title:||Prospective Study of Dietary Factors, BMI, and Risk of Asthma in Children|
|Study Start Date :||January 2007|
|Actual Primary Completion Date :||December 2008|
|Actual Study Completion Date :||December 2008|
- incident asthma [ Time Frame: childhood ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00454415
|United States, Massachusetts|
|Channing Laboratory, Brigham and Women's Hospital|
|Boston, Massachusetts, United States, 02115|
|Principal Investigator:||Carlos A. Camargo, MD, DrPH||Channing Laboratory, Brigham and Women's Hospital|