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Renal Transporters After Renal Transplantation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00427024
Recruitment Status : Unknown
Verified February 2007 by University Hospital Muenster.
Recruitment status was:  Not yet recruiting
First Posted : January 26, 2007
Last Update Posted : February 6, 2007
Sponsor:
Information provided by:
University Hospital Muenster

Brief Summary:
Previous studies in animals revealed, that the activity of certain transporters along the nephron is changed with acute rejection after renal transplantation. We intend to investigate underlying mechanisms occurring in man in renal biopsy specimens obtained from patients because of acute rejection of the transplant or chronic transplant nephropathy.

Condition or disease
Kidney Transplantation Host vs Graft Reaction

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Study Type : Observational
Enrollment : 200 participants
Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: Study of Renal Transporters and Their Regulators After Renal Transplantation
Study Start Date : February 2007
Study Completion Date : February 2009

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • individuals transplanted with a donor kidney
  • individuals with acute transplant rejection

Exclusion Criteria:

  • pregnancy
  • malignant disease
  • HIV infection

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00427024


Contacts
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Contact: Gert Gabriëls, PD Dr. med. 0049-251-83-47676 gabrie@uni-muenster.de
Contact: Hermann Pavenstädt, Prof. Dr. med. 0049-251-83-47516 Hermann.Pavenstaedt@ukmuenster.de

Locations
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Germany
University Hospital Münster
Münster, Germany, 48149
Contact: Gert Gabriëls, PD Dr. med.    0049-251-83-47676    gabrie@uni-muenster.de   
Contact: Hermann Pavenstädt, Prof. Dr. med.    0049-83-251-47516    Hermann.Pavenstaedt@ukmuenster.de   
Principal Investigator: Gert Gabriëls, PD Dr. med.         
Sponsors and Collaborators
University Hospital Muenster
Investigators
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Study Chair: Gert Gabriëls, PD Dr. med. University Hospital Münster

Publications:
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ClinicalTrials.gov Identifier: NCT00427024    
Other Study ID Numbers: NTX + Transport
First Posted: January 26, 2007    Key Record Dates
Last Update Posted: February 6, 2007
Last Verified: February 2007
Keywords provided by University Hospital Muenster:
renal transplantation
acute rejection
transport
transporter
acute rejection after renal transplantation