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Trial record 58 of 1206 for:    Adenosine

Effectiveness of Calcium Channel Blockers and Adenosine in the Emergency Management of SVT

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00413712
Recruitment Status : Completed
First Posted : December 20, 2006
Last Update Posted : February 10, 2017
Information provided by (Responsible Party):
Singapore General Hospital

Brief Summary:
The purpose of this study is to determine the efficacy and effectiveness of calcium channel blockers and adenosine in the treatment of Supraventricular Tachycardia.

Condition or disease Intervention/treatment Phase
Supraventricular Tachycardia Drug: Calcium Channel Blocker & Adenosine Phase 4

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Study Type : Interventional  (Clinical Trial)
Enrollment : 206 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Comparism Between Efficacy and Effectiveness Between Slow Infusion of Calcium Channel Blockers and Intravenous Bolus Adenosine in the Management of Supraventricular Tachycardia in the Emergency Department.
Study Start Date : January 1997
Study Completion Date : March 2001

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Calcium

Primary Outcome Measures :
  1. Conversion to the sinus rhythm.

Secondary Outcome Measures :
  1. Recurrence of SVT
  2. Stability of vital signs

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   10 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • More than 10 years old
  • Electrocardiographic diagnosis of SVT
  • SVT not converted by the vagal manoeuvres

Exclusion Criteria:

  • Signs of impaired cerebral perfusion
  • Signs of pulmonary oedema
  • Subsequent diagnosis of other types of arrythmias rather than SVT
  • pregnancy by history

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00413712

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Singapore General Hospital
Singapore, Singapore, 62223322
Sponsors and Collaborators
Singapore General Hospital
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Principal Investigator: Lim S Han, MBBS,FRCS Department of Emergency Medicine, Singapore General Hospital


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Responsible Party: Singapore General Hospital Identifier: NCT00413712    
Other Study ID Numbers: IRB18/1997
First Posted: December 20, 2006    Key Record Dates
Last Update Posted: February 10, 2017
Last Verified: February 2017
Keywords provided by Singapore General Hospital:
Supraventricular Tachycardia
Calcium Channel Blockers
Additional relevant MeSH terms:
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Tachycardia, Supraventricular
Disease Attributes
Pathologic Processes
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Cardiac Conduction System Disease
Calcium, Dietary
Calcium Channel Blockers
Calcium-Regulating Hormones and Agents
Physiological Effects of Drugs
Bone Density Conservation Agents
Sensory System Agents
Peripheral Nervous System Agents
Anti-Arrhythmia Agents
Vasodilator Agents
Purinergic P1 Receptor Agonists
Purinergic Agonists
Purinergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Membrane Transport Modulators