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Cyclosporine A in the Treatment of Juvenile Idiopathic Arthritis (JIA) Associated Chronic Anterior Uveitis

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ClinicalTrials.gov Identifier: NCT00404482
Recruitment Status : Completed
First Posted : November 28, 2006
Last Update Posted : June 3, 2009
Sponsor:
Information provided by:
St. Franziskus Hospital

Study Description
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Brief Summary:
Juvenile idiopathic arthritis (JIA) is often associated with chronic anterior uveitis. Presence of vision threatening complications may indicate immunosuppressive therapy. In this study, the experience with cyclosporine A (CsA) as mono- or combination-therapy is analyzed.

Condition or disease Intervention/treatment
Uveitis Juvenile Idiopathic Arthritis Drug: Cyclosporine A

Study Design
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Study Type : Observational
Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Efficacy and Adverse Effects of Cyclosporine A in the Treatment of Chronic Anterior Uveitis in Patients With Juvenile Idiopathic Arthritis
Study Start Date : January 1991
Study Completion Date : August 2006

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Groups and Cohorts
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Outcome Measures
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Eligibility Criteria
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Ages Eligible for Study:   up to 16 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients with JIA and cyclosporin A therapy
Criteria

Inclusion Criteria:

  • uveitis
  • JIA
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00404482


Locations
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Germany
Deutsches Zentrum für Kinder- und Jugendrheumatologie
Garmisch-Partenkirchen, Germany
Department of Ophthalmology at St.-FranziskusHospital
Münster, Germany
Kinder und Jugendrheumatologie St. Josef Stift
Sendenhorst, Germany
Sponsors and Collaborators
St. Franziskus Hospital
Investigators
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Principal Investigator: Christoph Tappeiner, MD Department of Ophthalmology at University Bern - Inselspital
More Information
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ClinicalTrials.gov Identifier: NCT00404482    
Other Study ID Numbers: 01-1106
First Posted: November 28, 2006    Key Record Dates
Last Update Posted: June 3, 2009
Last Verified: June 2009
Keywords provided by St. Franziskus Hospital:
uveitis
jia
Cyclosporine A
MTX
Additional relevant MeSH terms:
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Arthritis
Arthritis, Juvenile
Uveitis
Uveitis, Anterior
Iridocyclitis
Joint Diseases
Musculoskeletal Diseases
Uveal Diseases
Eye Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases
Panuveitis
 Iris Diseases
Cyclosporine
Cyclosporins
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antifungal Agents
Anti-Infective Agents
Dermatologic Agents
Antirheumatic Agents
Calcineurin Inhibitors