COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Prescription Methods Assessment Project (PMAP)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00393653
Recruitment Status : Terminated (Funding ended early)
First Posted : October 29, 2006
Last Update Posted : May 10, 2011
Information provided by:
American Academy of Family Physicians

Brief Summary:
The purpose of this study is to evaluate whether a novel prescription method (N-of-1 intervention)can be successfully integrated into primary care practices and to examine the effects of this prescription method on selected patient health outcomes (e.g.., medication compliance, medication costs, symptom management, satisfaction of physician/patient visit, etc.) in patients with a uncontrolled or new diagnosis of Osteoarthritis or Chronic Heartburn (GERD).

Condition or disease Intervention/treatment Phase
Osteoarthritis Gastroesophageal Reflux Disease Procedure: N-of-1 prescription method Not Applicable

Show Show detailed description

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 800 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Prescription Methods Assessment Project (PMAP)
Study Start Date : October 2006
Actual Study Completion Date : May 2007

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. Side-effects and adverse events (base-line, 3 and 6 months)

Secondary Outcome Measures :
  1. Symptoms of condition and health related issues (i.e., satisfaction of doctor visit, self-efficacy)at baseline, 3 and 6 months
  2. Patient medication information and adherence to prescription(s) at 3 and 6 months

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • at least 18 years old
  • capable of giving informed consent
  • a new diagnosis or uncontrolled symptoms of either osteoarthritis or gastroesophageal reflux disease
  • if new diagnosis or uncontrolled osteoarthritis, patient must have condition in knee or hip (need not be isolated)

Exclusion Criteria:

  • too ill to participate
  • not capable of giving informed consent
  • not able to be contacted via phone for study follow-up
  • unable to read English, including blindness
  • if treating physician considers patient to have medical conditions that would cause the patient to be placed at risk by trial participation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00393653

Layout table for location information
United States, Kansas
American Academy of Family Physicians National Research Network
Leawood, Kansas, United States, 66211
Sponsors and Collaborators
American Academy of Family Physicians
Layout table for investigator information
Principal Investigator: Wilson D Pace, MD American Academy of Family Physicians
Additional Information:
Layout table for additonal information Identifier: NCT00393653    
Other Study ID Numbers: 06-016
First Posted: October 29, 2006    Key Record Dates
Last Update Posted: May 10, 2011
Last Verified: May 2011
Keywords provided by American Academy of Family Physicians:
gastroesophageal reflux disease
practice-based research
N-of-1 trial
single-patient trial
Additional relevant MeSH terms:
Layout table for MeSH terms
Gastroesophageal Reflux
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Esophageal Motility Disorders
Deglutition Disorders
Esophageal Diseases
Gastrointestinal Diseases
Digestive System Diseases