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The purpose of this study is to compare the effectiveness of 2 different sequences of polychemotherapy among carrying patients of a adenocarcinoma of the stomach or cardia locally advanced or metastatic.
Condition or disease
Stomach CancerNeoplasm Metastasis
Drug: ECCDrug: FOLFIRI
To compare the effectiveness of two different sequences of polychemotherapy among carrying patients of a adenocarcinoma of the stomach or cardia locally advanced or metastatic.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
age = 18 years old
patients carrying a adenocarcinoma of the stomach or cardia histologically proven
locally advanced tumour which may not be treated surgically or metastatic tumour
the patients having a stenosante tumour responsible for a disphagy had to have a tumoral ablation or a prosthesis or a probe of food,
measurable lesions according to criteria RECIST (specify measurement by spiral scanner of largest diameter of with less the one lesion of size higher than 1 cm) or appraisable but nonmeasurable (lesions < 1 cm, ascite, pleural effusion...)
general state WHO < 2
absence of insufficiency cardiac or coronary symptomatic
absence of previous chemotherapy other that auxiliary stopped since more than 6 months