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The Efficacy of Selective Laser Trabeculoplasty

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00347893
Recruitment Status : Unknown
Verified June 2006 by Glaucoma Research & Education Group.
Recruitment status was:  Recruiting
First Posted : July 4, 2006
Last Update Posted : July 4, 2006
PharmaLogic Development, Inc.
Information provided by:
Glaucoma Research & Education Group

Brief Summary:
Selective laser trabeculoplasty (SLT) is a new method to reduce intraocular pressure in eyes with open angle glaucoma or ocular hypertension. SLT may also be effective for cases with previously failed ALT procedures. We will study the efficacy and safety of the SLT procedure.

Condition or disease Intervention/treatment
Primary Open Angle Glaucoma Ocular Hypertension Pseudo-Exfoliative Glaucoma Pigment Dispersion Glaucoma Procedure: Selective laser trabeculoplasty

Detailed Description:
Selective laser trabeculoplasty (SLT) has been shown to be a safe, well tolerated, and effective intraocular pressure reduction therapy for several forms of open-angle glaucoma. SLT produces significantly less disturbance to the trabecular meshwork and is theoretically more repeatable than the ALT procedure. This retrospective research will begin with cases treated in 2001. It will evaluate whether SLT is effective for patients who have had prior treatment with ALT and it will determine whether the IOP lowering effect is sustainable over time. It will also assess the efficacy of repeated SLT procedures.

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Study Type : Observational
Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Retrospective
Official Title: Clinical Results of Selective Laser Trabeculoplasty in Treatment of Open Angle Glaucoma
Study Start Date : May 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Glaucoma

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Patients with primary open angle glaucoma, ocular hypertension, pseudo exfoliative glaucoma, pigment dispersion glaucoma

Exclusion Criteria:

  • History of prior invasive glaucoma surgery

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00347893

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United States, California
Glaucoma Center of San Francisco Recruiting
San Francisco, California, United States, 94105
Contact: Martha T Klufas, OD    415-986-0835   
Principal Investigator: Andew G. Iwach, M.D.         
Sub-Investigator: Jing Ming Shi, M.D.         
Sub-Investigator: Terri Pickering, M.D.         
Sponsors and Collaborators
Glaucoma Research & Education Group
PharmaLogic Development, Inc.
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Principal Investigator: Andrew G. Iwach, M.D. Glaucoma Research & Education Group
Layout table for additonal information Identifier: NCT00347893    
Other Study ID Numbers: 22222
First Posted: July 4, 2006    Key Record Dates
Last Update Posted: July 4, 2006
Last Verified: June 2006
Keywords provided by Glaucoma Research & Education Group:
Primary open angle glaucoma
Ocular hypertension
Pseudo-exfoliative glaucoma
Pigment Dispersion glaucoma
selective laser trabeculoplasty
intraocular pressure
Additional relevant MeSH terms:
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Glaucoma, Open-Angle
Ocular Hypertension
Vascular Diseases
Cardiovascular Diseases
Eye Diseases