Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin C
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ClinicalTrials.gov Identifier: NCT00346489 |
Recruitment Status :
Completed
First Posted : June 30, 2006
Last Update Posted : December 27, 2007
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Glaucoma | Drug: 5-fluorouracil Drug: Mitomycin C | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Enrollment : | 70 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double |
Primary Purpose: | Treatment |
Official Title: | Intermediate Term Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin c in Trabeculectomy Surgery. |
Study Start Date : | September 2004 |
Actual Primary Completion Date : | August 2007 |
Actual Study Completion Date : | August 2007 |
- Pressure Control
- Mitomycin Complications

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Ages Eligible for Study: | Child, Adult, Older Adult |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Only patients deemed successful as 36 months will be included. These patients will have participated in the randomized prospective study trial comparing intraoperative 5-FU and mitomycin C in primary trabeculectomy.
Exclusion Criteria:
- Only patients deemed successful as 36 months will be included. These patients will have participated in the randomized prospective study trial comparing intraoperative 5-FU and mitomycin C in primary trabeculectomy.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00346489
United States, Indiana | |
University Hospital and Outpatient Center | |
Indianapolis, Indiana, United States, 46202 | |
IU Eye at Carmel | |
Indianapolis, Indiana, United States, 46290 |
Principal Investigator: | Louis B Cantor, MD | IUPUI/Clarian |
ClinicalTrials.gov Identifier: | NCT00346489 |
Other Study ID Numbers: |
0409-60 |
First Posted: | June 30, 2006 Key Record Dates |
Last Update Posted: | December 27, 2007 |
Last Verified: | December 2007 |
Trabeculectomy 5-fluorouracil Mitomycin C |
Glaucoma Ocular Hypertension Eye Diseases Fluorouracil Mitomycins Mitomycin Antimetabolites Molecular Mechanisms of Pharmacological Action Antimetabolites, Antineoplastic |
Antineoplastic Agents Immunosuppressive Agents Immunologic Factors Physiological Effects of Drugs Antibiotics, Antineoplastic Alkylating Agents Nucleic Acid Synthesis Inhibitors Enzyme Inhibitors |