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Health Outcomes in Rheumatoid Arthritis (HORA)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00346411
Recruitment Status : Completed
First Posted : June 29, 2006
Last Update Posted : October 5, 2017
Information provided by (Responsible Party):
Johns Hopkins University

Brief Summary:
This research is being done to help us learn about how different factors related to treatment affect rheumatoid arthritis (RA). This is not a treatment study. We will follow the patient for one year as he or she receives usual treatment from his or her rheumatologist. Up to 360 adults with RA may join this study.

Condition or disease
Rheumatoid Arthritis

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Study Type : Observational
Actual Enrollment : 164 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Health Outcomes in Rheumatoid Arthritis
Actual Study Start Date : September 1, 2005
Actual Primary Completion Date : December 12, 2011
Actual Study Completion Date : December 12, 2011

Resource links provided by the National Library of Medicine

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   19 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Individuals diagnosed with rheumatoid arthritis and receiving treatment for this condition from a rheumatologist

Inclusion Criteria:

  • Males and females age 19 or older
  • Current active, adult-onset rheumatoid arthritis who meet American College of Rheumatology (ACR) criteria for RA and have: (ACR functional class I-III), defined as:
  • 3 or more swollen or tender joints and
  • Morning stiffness of 45min or longer
  • OR judged by their rheumatologist to have active disease
  • No evidence of other inflammatory diseases (e.g., Crohn's, IBS)
  • Functional class I, II or III

Exclusion Criteria:

  • Individuals with significant cardiovascular disease (CHF, stroke, MI)
  • Unwilling to have medications monitored and/or comply with protocol
  • Not fluent in English
  • Planning to move from area within next year or change health insurance (which would preclude ongoing care by a Johns Hopkins rheumatologist)
  • Enrolled in study evaluating efficacy of new or existing RA medications

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00346411

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United States, Maryland
Johns Hopkins Bayview Campus
Baltimore, Maryland, United States, 21224
Sponsors and Collaborators
Johns Hopkins University
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Principal Investigator: Susan Bartlett, PhD Johns Hopkins School of Medicine
Principal Investigator: Cynthia S Rand, PhD Johns Hopkins University
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Responsible Party: Johns Hopkins University Identifier: NCT00346411    
Other Study ID Numbers: NA_00001359
First Posted: June 29, 2006    Key Record Dates
Last Update Posted: October 5, 2017
Last Verified: October 2017
Keywords provided by Johns Hopkins University:
rheumatoid arthritis
Additional relevant MeSH terms:
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Arthritis, Rheumatoid
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases