Investigating Age-Related Macular Degeneration
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|ClinicalTrials.gov Identifier: NCT00342251|
Recruitment Status : Completed
First Posted : June 21, 2006
Last Update Posted : July 2, 2017
Age-related macular degeneration (ARMD) affects older Americans and can lead to irreversible blindness. Although the cause if ARMD is unclear, it appears to be a condition that is affected by both genetic and environmental influences.
The purpose of this study is to examine an Amish community to investigate genetic factors in the development of ARMD.
Study participants will be 1,000 members, ages 50 and older, of the Old Order Amish community in Lancaster and Franklin counties in Pennsylvania. Each will undergo a 30-minute dilated eye exam during which an ophthalmologist or optometrist will take digital images of the macula and optic disc. Depending on the results of their eye exam, participants may be asked to give a blood sample as well. They will also complete a brief questionnaire about personal exposure related to occupation, sunlight and smoking.
|Condition or disease|
|Age-Related Macular Degeneration|
|Study Type :||Observational|
|Estimated Enrollment :||3000 participants|
|Official Title:||Age-Related Macular Degeneration: A Genetic Epidemiology Study in the Amish|
|Study Start Date :||June 20, 2003|
|Study Completion Date :||April 4, 2012|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00342251
|United States, Pennsylvania|
|University of Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19104-6056|
|Principal Investigator:||Susan Vitale, Ph.D.||National Eye Institute (NEI)|