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Cognitive Behavioral Therapy for Pathological Gambling

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00337753
Recruitment Status : Completed
First Posted : June 16, 2006
Last Update Posted : January 5, 2010
National Institute of Mental Health (NIMH)
Information provided by:
University of Minnesota

Brief Summary:
The purpose of the study is to evaluate a new form of counseling for pathological gambling and to see if the counseling is more effective than attending Gamblers Anonymous.

Condition or disease Intervention/treatment Phase
Pathological Gambling Behavioral: Cognitive Behavioral Therapy Behavioral: Wait-list Phase 2

Detailed Description:

Subjects will be assigned to counseling or be given a referral list of available Gamblers Anonymous meetings at the first visit based on answers to questions. Assignment to counseling or Gamblers Anonymous will be randomly selected (i.e. chance) with an equal chance of receiving either one. For those assigned to counseling, you will meet with the therapist for 60 minutes weekly. You will receive 5 sessions of counseling.

All subjects will be assessed with gambling questionnaires twice during the 5-week period and again at 3 and 6 months following the 5-week period.

For those assigned to Gamblers Anonymous, they will be offered 5 weeks of counseling at the end of the 6-month follow-up.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 76 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Cognitive Behavioral Therapy for Pathological Gambling
Study Start Date : June 2006
Actual Primary Completion Date : June 2009
Actual Study Completion Date : June 2009

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Active Comparator: Cognitive Behavioral Therapy
Weekly Cognitive Behavior therapy
Behavioral: Cognitive Behavioral Therapy
5-weeks of Cognitive Behavioral Therapy
Other Name: CBT

Subjects in wait-list for six-weeks
Behavioral: Wait-list
subjects assigned to wait-list condition for six-weeks

Primary Outcome Measures :
  1. PG-YBOCS [ Time Frame: At each visit prior to and after therapy has been completed ]

Secondary Outcome Measures :
  1. Time spent gambling [ Time Frame: At each visit prior to and after therapy has been completed ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. Outpatient men and women age 18 to 75
  2. Presence of current DSM-IV pathological gambling for at least 6 months duration
  3. PG is the most problematic psychiatric disorder (in the patient's and clinician's opinion) and the primary reason for seeking treatment
  4. Minimum score of >5 on the South Oaks Gambling Screen which reflects gambling severity consistent with pathological gambling

Exclusion Criteria:

  1. Current clinically significant suicidality, severe depression (a score of ≥ 19 on the Hamilton Rating Scale for Depression, 17-item version)(30) or any other disorder requiring immediate intervention
  2. Presence of any clinical features requiring a higher level of care than outpatient treatment
  3. Cognitive impairment that interferes with the capacity to engage in CBT or to provide informed consent
  4. DSM-IV substance abuse or dependence within the past 3 months (see Screening Visit)
  5. Current Axis I diagnosis of bipolar disorder or psychotic disorder
  6. Previous treatment of CBT for PG (duration of at least 6 sessions); because CBT is not widely used for PG, a minimum of 6 treatments will be rare.
  7. Current use of psychotropic medications or within 2 months prior to study entry.
  8. Current participation in Gambler's Anonymous (GA).

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00337753

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United States, Minnesota
University of Minnesota Medical Center
Minneapolis, Minnesota, United States, 55454
Sponsors and Collaborators
University of Minnesota
National Institute of Mental Health (NIMH)
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Principal Investigator: Jon E Grant, MD, JD University of Minnesota

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Responsible Party: Jon E. Grant, University of Minnesota Identifier: NCT00337753    
Other Study ID Numbers: 0503M68191
K23MH069754-01A1 ( U.S. NIH Grant/Contract )
First Posted: June 16, 2006    Key Record Dates
Last Update Posted: January 5, 2010
Last Verified: January 2010
Keywords provided by University of Minnesota:
Additional relevant MeSH terms:
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Disruptive, Impulse Control, and Conduct Disorders
Mental Disorders