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Efficacy of Cyclosporine Ophthalmic Emulsion in the Treatment of Dry Eye Syndrome in Contact Lens Wearers

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ClinicalTrials.gov Identifier: NCT00335114
Recruitment Status : Completed
First Posted : June 8, 2006
Last Update Posted : June 9, 2006
Sponsor:
Information provided by:
University of Alabama at Birmingham

Brief Summary:
Cyclosporine Ophthalmic Emulsion is currently used in the treatment of dry eye syndrome. Contact lens wearers frequently suffer from dry eye syndrome. The purpose of this study is to evaluate cyclosporine ophthalmic emulsion verses re-wetting drops in the relief of dry eye symptoms in contact lens wearers

Condition or disease Intervention/treatment Phase
Contact Lens Wearers With Dry Eye Syndrome Drug: cyclosporine ophthalmic emulsion Not Applicable

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Study Type : Interventional  (Clinical Trial)
Enrollment : 40 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Efficacy of Cyclosporine Ophthalmic Emulsion in the Treatment of Dry Eye Syndrome in Contact Lens Wearers
Study Start Date : November 2005
Study Completion Date : April 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Eye Wear




Primary Outcome Measures :
  1. Ocular exams and questionnaires at baseline and at 3 months will determine
  2. the effect of cyclosporine on dry eye syndrome.

Secondary Outcome Measures :
  1. Increased contact lens wearing time due to a decrease in severity
  2. of dry eye symptoms


Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • contact lens wearer
  • clinical diagnosis of dry eye syndrome

Exclusion Criteria:

-


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00335114


Locations
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United States, Alabama
UAB Ophthalmology Services Foundation
Birmingham, Alabama, United States, 35233
Sponsors and Collaborators
University of Alabama at Birmingham
Investigators
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Principal Investigator: Carol E Rosenstiel, OD University of Alabama at Birmingham

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ClinicalTrials.gov Identifier: NCT00335114     History of Changes
Other Study ID Numbers: F051025017
First Posted: June 8, 2006    Key Record Dates
Last Update Posted: June 9, 2006
Last Verified: June 2006

Keywords provided by University of Alabama at Birmingham:
cyclosporine, dry eye syndrome, contact lens

Additional relevant MeSH terms:
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Keratoconjunctivitis Sicca
Dry Eye Syndromes
Syndrome
Disease
Pathologic Processes
Keratoconjunctivitis
Conjunctivitis
Conjunctival Diseases
Eye Diseases
Keratitis
Corneal Diseases
Lacrimal Apparatus Diseases
Cyclosporine
Cyclosporins
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antifungal Agents
Anti-Infective Agents
Dermatologic Agents
Antirheumatic Agents
Calcineurin Inhibitors