Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine
|ClinicalTrials.gov Identifier: NCT00328900|
Recruitment Status : Unknown
Verified April 2007 by Rikshospitalet University Hospital.
Recruitment status was: Recruiting
First Posted : May 24, 2006
Last Update Posted : June 1, 2012
|Condition or disease||Intervention/treatment||Phase|
|Hemorrhoids Fissure in Ano||Drug: Administration of 0,7 mg of atropine Device: Measurement of skin conductance with Pain detector||Not Applicable|
Skin conductance (SC), in terms of numbers of skin conduction fluctuations (NSCF), amplitude and mean skin conductance level, reflect the activity in the sympathetic postganglionic cholinergic fibers which innervate the palmar and plantar sweat glands. Skin conductance, especially numbers of skin conductance fluctuations, may be a promising tool to monitor anesthesia. Atropine, an anticholinergic agent, acts as an antagonist on the muscarinic receptors of the sweat glands and inhibits their secretion in a dose-dependent way. The aim of this study was to find out to what degree SC is influenced by i.v. administration of atropine.
Study hypothesis: SC is not influenced by i.v. administration of atropine.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||24 participants|
|Intervention Model:||Factorial Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||January 2006|
- Number of skin conductance fluctuations
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00328900
|Contact: Hanne Storm, PhD||+47 email@example.com|
|Ulleval University Hospital||Recruiting|
|Oslo, Norway, 0407|
|Contact: Hanne Storm, PhD +47 23074398 firstname.lastname@example.org|
|Study Director:||Hanne Storm, PhD||Rikshospitalet University Hospital|