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The Genetic Basis for Familial Cardiomyopathy in Patients With Idiopathic Cardiomyopathy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00322582
Recruitment Status : Terminated (no financial resources were available to complete the study)
First Posted : May 8, 2006
Last Update Posted : January 25, 2012
Information provided by (Responsible Party):
Offer Amir, Carmel Medical Center

Brief Summary:
In many of the patients with cardiomyopathy, the etiology is not clear . In about 30% there is a family history of cardiomyopathy .Our aim is to study the genetics basis for these patients with cardiomyopathy with no clear etiology and who have a first degree family relative with cardiomyopathy as well.

Condition or disease

Detailed Description:
A total of 950 blood samples will be collected from patients with idiopathic cardiomyopathy and their relatives and will be analysed for genetics analysis.

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Study Type : Observational
Actual Enrollment : 41 participants
Observational Model: Family-Based
Time Perspective: Prospective
Official Title: Open Labeled of the Study the Genetic Basis for Familial Cardiomyopathy in Patients With Idiopathic
Study Start Date : May 2007
Actual Primary Completion Date : February 2009
Actual Study Completion Date : February 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cardiomyopathy

Biospecimen Retention:   Samples With DNA
Blood samples

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
History of cardiomyopathy

Inclusion Criteria:

  • history of cardiomyopathy
  • etiology not known
  • family history of cardiomyopathy
  • ability to understand and sign the informed consent

Exclusion Criteria:

  • refusal to participate
  • pregnancy
  • current participation in another active treatment study

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00322582

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Carmel Medical Center
Haifa, Israel, 34362
Sponsors and Collaborators
Carmel Medical Center
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Study Director: Offer Amir, MD Lady Davis Carmel Hospital
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Responsible Party: Offer Amir, Offer Amir, MD, Carmel Medical Center, Carmel Medical Center Identifier: NCT00322582    
Other Study ID Numbers: GEN/ICM
First Posted: May 8, 2006    Key Record Dates
Last Update Posted: January 25, 2012
Last Verified: January 2007
Keywords provided by Offer Amir, Carmel Medical Center:
familial cardiomyopathy
genetics analysis
Additional relevant MeSH terms:
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Heart Diseases
Cardiovascular Diseases