Exercise Therapy and Patient Education for Individuals With Hip Osteoarthritis of the Hip. A Case-Control Study
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|ClinicalTrials.gov Identifier: NCT00319124|
Recruitment Status : Completed
First Posted : April 27, 2006
Last Update Posted : March 2, 2016
To identify differences between patients with OA of the hip in an early stage and a healthy control group.
Hypothesis 1.1 There are significant differences between patients with OA of the hip in an early stage and a healthy control group in terms of functional capacity, biomechanical / kinematic variables, muscle strength and range of motion.
Osteoarthritis (OA) is by far the most prevalent joint disorder today. The knee and the hip are large joints to be targeted and is an important cause of pain and disability. In knee OA, it is shown that significant risk factors in developing the disease are quadriceps weakness, joint instability, and changes in joint loading. A few studies on hip OA have shown altered gait pattern, which affect joint loading, and one study has shown weakness in abductors, adductors and flexors around the hip. As joint loading and muscle weakness are important factors in the development in knee OA, it might as well be factors influencing OA in the hip. The purpose of this case-control studies was to compare hip OA patients to a healthy control group regarding biomechanical and clinical differences. Patients with hip pain, activity limitations (Harris Hip Score 60-95 p) and radiographically verified hip OA was included. The healthy control group will have a Harris Hip Score of 100 p. One hundred and ten patients and fifty controls will be asked to fill in questionnaires on pain, stiffness and physical function (WOMAC), quality-of-life (SF-36 v2), self-efficacy (Lorigue), and activity (PASE) in addition to perform 6-minute walk test, sub-maximal cardiovascular function, strength, and hip range of motion tests. Additionally, Qualisys Pro reflex 3D motion analysis system will be used during walking, one-leg standing, and raising from a chair on a sub-group of 40 patients and 20 controls.
|Condition or disease|
Show Detailed Description
|Study Type :||Observational|
|Actual Enrollment :||52 participants|
|Observational Model:||Case Control|
|Official Title:||Evaluation of Function and Effect of Exercise in Patients With Osteoarthritis of the Hip.A Case-control Study.|
|Study Start Date :||April 2005|
|Actual Primary Completion Date :||August 2008|
|Actual Study Completion Date :||October 2010|
Patients with hip Osteoarthritis
Healthy controls without hip osteoarthritis
- Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) [ Time Frame: Baseline ]
- SF-36 (quality of life) [ Time Frame: Baseline ]
- PASE (activity score) [ Time Frame: Baseline ]
- muscle strength tests (Cybex 6000) [ Time Frame: Baseline ]
- gait analysis (biomechanical analysis) [ Time Frame: Baseline ]
- 6 minutes walking test [ Time Frame: Baseline ]
- Åstrand's bike test [ Time Frame: Baseline ]
- Range of Motion (goniometer) [ Time Frame: Baseline ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00319124
|NAR- Department of Orthopaedics, Oslo University Hospital & Hjelp24NIMI|
|Oslo, Norway, 0407|
|Principal Investigator:||May Arna Risberg, PT,PhD||NAR-Department of Orthopaedics, Oslo University Hospital|