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Motion Analysis of Sit-to-Stand Movements in Children With Spastic Diplegia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00314301
Recruitment Status : Unknown
Verified April 2006 by Far Eastern Memorial Hospital.
Recruitment status was:  Not yet recruiting
First Posted : April 13, 2006
Last Update Posted : April 17, 2006
National Taiwan University
Information provided by:
Far Eastern Memorial Hospital

Brief Summary:
The purpose of this study is to compare movement variations before and after the loaded training, with kinematics, kinetics, and electromyography, in children with spastic diplegia and to further discuss mechanisms of the loaded training.

Condition or disease Intervention/treatment Phase
Cerebral Palsy Device: loaded sit-to-stand training Not Applicable

Detailed Description:

Subjects: This study will recruit twenty children who are aged between 5 and 12 years, with spastic diplegia, and without having major surgeries or botulinum toxin injection on lower extremities during the past 6 months prior to participate in this study.

Methods: The Vicon 250 motion analysis system, 3 AMTI force platforms and the EMG recording system will be used to collect data of sit-to-stand (STS) movements. Baseline, pre- and post-training evaluations will be carried out. The duration of the baseline and pre-training evaluations is 2 months. The training period will take about 6 weeks. Each evaluation will take two separate days to accomplish. On the first day, the STS1RM of individual children was determined. On the second day, kinematic and kinetic data of STS movements in natural and loaded (applying load of 50% STS1RM during STS movements) conditions were collected. Data of smoothness, maximal extension moment and around hip and knee joints, onset time of lower extremity muscles will then be calculated. Results of each evaluation will be used for further comparison.

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Study Type : Interventional  (Clinical Trial)
Enrollment : 20 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Educational/Counseling/Training
Official Title: Motion Analysis of Sit-to-Stand Movements in Children With Spastic Diplegia Before and After Loaded Sit-to-Stand Training
Study Start Date : April 2006
Study Completion Date : September 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cerebral Palsy

Primary Outcome Measures :
  1. kinematic measures of lower extremity and the whole body
  2. kinetic measures of lower extremity and the whole body
  3. electromyographic measures of lower extremity and the whole body

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   5 Years to 12 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosed as spastic diplegia
  • Aged between 5 and 12 years
  • Able to perform the STS movements without assistance
  • Able to cooperate and understand commands given

Exclusion Criteria:

  • Severe musculoskeletal deformity or pain on lower extremities
  • Botulism injection in the past 3 months or major operations in the preceding 6 months on lower extremities
  • Uncontrolled epilepsy
  • Major sensory deficits, such as blindness or deafness

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00314301

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Contact: Yuh-Ting Lin, MSc 866-2-8966-7000 ext 1411
Contact: Jao-Shwann Liang, MD 866-2-8966-7000 ext 1411

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National Taiwan University Hospital
Taipei, Taiwan, 100
Contact: Hua-Fang Liao, MPH    886-2-3322\8136   
Principal Investigator: Yuh-Ting Lin, MSc         
Sponsors and Collaborators
Far Eastern Memorial Hospital
National Taiwan University
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Principal Investigator: Yuh-Ting Lin, MSc Research Ethics Review Committee of the Far Eastern Memorial Hospital

Layout table for additonal information Identifier: NCT00314301    
Other Study ID Numbers: 94023
First Posted: April 13, 2006    Key Record Dates
Last Update Posted: April 17, 2006
Last Verified: April 2006
Keywords provided by Far Eastern Memorial Hospital:
cerebral palsy
Additional relevant MeSH terms:
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Cerebral Palsy
Brain Damage, Chronic
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases