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Microbiological Examination of Children Operated for Congenital Lacrimal Stenosis

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ClinicalTrials.gov Identifier: NCT00312689
Recruitment Status : Unknown
Verified April 2007 by University Hospital Muenster.
Recruitment status was:  Active, not recruiting
First Posted : April 10, 2006
Last Update Posted : April 12, 2007
Sponsor:
Information provided by:
University Hospital Muenster

Brief Summary:

Children with congenital lacrimal stenosis are treated by probing and intubation of the lacrimal drainage system.

Hypothesis: Microbiological findings at the time of insertion and removal of the silicon intubation have an influence on the clinical outcome and success rate of the surgical treatment. Microbiological specimens are taken from conjunctiva and nasal mucosa during the two procedures under general anaesthesia and from the silicon tube after removal and examined for bacterial contamination.


Condition or disease
Congenital Lacrimal Stenosis

Detailed Description:
Children (age 0-14 years) with congenital lacrimal stenosis in whom probing and intubation of the lacrimal drainage system is indicated are included the study after informed written consent by their parents. Microbiological specimens are taken bilaterally from conjunctiva and nasal mucosa during the two procedures under general anaesthesia (insertion and removal of the silicon intubation) and from the silicon tube after removal. Specimens are examined for bacterial contamination. Microbiological findings are correlated with clinical data about the further clinical course and especially the success of the surgical treatment.

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Study Type : Observational
Enrollment : 120 participants
Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Microbiological Examination of Children Operated for Congenital Lacrimal Stenosis
Study Start Date : March 2006
Estimated Study Completion Date : April 2007




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Ages Eligible for Study:   up to 14 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria: age 0-14 years, congenital lacrimal stenosis, informed consent by the parents -

Exclusion Criteria: none

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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00312689


Locations
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Germany
Augenklinik
Muenster, Germany, 48149
Sponsors and Collaborators
University Hospital Muenster
Investigators
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Principal Investigator: Annette Kolck, MD University Hospital Muenster

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ClinicalTrials.gov Identifier: NCT00312689     History of Changes
Other Study ID Numbers: Record 1
First Posted: April 10, 2006    Key Record Dates
Last Update Posted: April 12, 2007
Last Verified: April 2007

Keywords provided by University Hospital Muenster:
congenital
lacrimal
stenosis
bacteria
microbiological

Additional relevant MeSH terms:
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Constriction, Pathologic
Pathological Conditions, Anatomical