Study of the Effect of SR57667B in Patients With Alzheimer's Disease
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|ClinicalTrials.gov Identifier: NCT00285025|
Recruitment Status : Completed
First Posted : February 1, 2006
Last Update Posted : February 1, 2006
The primary objective is to demonstrate that SR57667B at the dose of 4 mg/day, in comparison to placebo, decreases the decline in cognitive performance and the global clinical decline over 1 year in patients with mild to moderate AD.
Secondary objectives are to assess the effect of SR57667B on functional decline and its safety/tolerability in patients with mild to moderate AD, and to document plasma concentrations of SR57667 in patients with mild to moderate AD.
|Condition or disease||Intervention/treatment||Phase|
|Alzheimer Disease||Drug: SR57667B||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||500 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||A Phase II, Multicenter, Multinational, Randomized, Double-Blind, Placebo-Controlled, Efficacy, Safety and Tolerability Study of SR57667B in Patients With Mild-to-Moderate Alzheimer's Disease|
|Study Start Date :||March 2005|
|Study Completion Date :||September 2005|
- ADAS-cog, CDR measured at baseline and at 2, 6, 9 and 12 months.
- MMSE, CGIC, ADCS-ADL, NPI measured at baseline and at 2, 6, 9 and 12 months.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00285025
|Study Chair:||Serge GAUTHIER, MD||Scientific Advisory Committee|
|Study Chair:||Jean-Marc ORGOGOZO, MD||Scientific Advisory Committee|
|Study Chair:||Philip SCHELTENS, MD||Scientific Advisory Committee|
|Study Chair:||Bengt WINBLAD, MD||Scientific Advisory Committee|