Study Evaluating MST-997 in Advanced Malignant Solid Tumors
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
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MST-997 is a taxane analog with the potential to treat subjects with a variety of tumor types. Preclinical data demonstrated that MST-997 inhibited tumor growth when administered intravenously (IV). This phase 1 dose escalation study is designed to evaluate the safety and tolerability of if IV MST-997 formulated in Polysorbate 80 Diluent can be safely administered on a weekly basis.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Documented diagnosis of malignant solid tumor with measurable disease
Life expectancy of at least 12 weeks
ECOG (Eastern Cooperative Oncology Group) performance status of 0,1,or 2
Recent major surgery, radiation therapy or anti-cancer treatment
History of any other prior malignancy within last 5 years