Comparison of Three Therapy-Based Interventions for Preventing Depression in Adolescents
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|ClinicalTrials.gov Identifier: NCT00258752|
Recruitment Status : Completed
First Posted : November 28, 2005
Last Update Posted : April 15, 2013
|Condition or disease||Intervention/treatment||Phase|
|Depression||Behavioral: IPT-AST Other: Enhanced IPT-AST Other: School counseling||Not Applicable|
Depression is a serious medical illness that is difficult to diagnose and treat, especially in children and adolescents. Signs of depression in children may include the following behaviors: pretending to be sick; refusing to go to school; clinging to a parent; or worrying that a parent may die. Older children may sulk, behave inappropriately at school, act in a negative or grouchy manner, or feel misunderstood. Because normal behaviors vary from one childhood stage to another, it can be difficult to determine whether a child is going through a temporary "phase" or is suffering from depression. This study will compare IPT-AST, Enhanced IPT-AST, and Usual Care for the prevention of adolescent depression.
Participation in this single-blind study will last approximately 21 months. Participants will be randomly assigned to receive either IPT-AST, Enhanced IPT-AST, or Usual Care for 12 weeks. IPT-AST is a school-based group intervention program that focuses on prevention, psychoeducation, and interpersonal skill-building. Enhanced IPT-AST will entail IPT-AST plus three parent-adolescent sessions. Usual Care will consist of standard treatments and will not include IPT-AST. Study visits will occur before and during the intervention at baseline and Weeks 6 and 12. Follow-up visits will occur 6, 12, and 18 months post-intervention. Study visit assessments will include depression symptoms, anxiety symptoms, psychiatric diagnoses, overall functioning, social adjustment, parent-child conflict, perceived support from parents and peers, and service utilization.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||57 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Prevention of Depression in Adolescents|
|Study Start Date :||November 2005|
|Actual Primary Completion Date :||January 2008|
|Actual Study Completion Date :||June 2009|
Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST)
IPT-AST is a school based group treatment program that focuses on prevention, psychoeducation, and interpersonal skill building.
Other: Enhanced IPT-AST
Enhanced IPT-AST entails IPT-AST plus three parent-adolescent sessions.
Active Comparator: 3
Typical school counseling
Other: School counseling
Usual care consists of standard treatments, including individual counseling with guidance counselor.
- Score on the Center for Epidemiologic Studies Depression Scale [ Time Frame: Measured immediately post-treatment and at Months 6, 12, and 18 follow-ups ]
- Rating on Children's Global Assessment Scale [ Time Frame: Measured immediately post-treatment and at Months 6, 12, and 18 follow-ups ]
- Depression diagnoses on the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) diagnostic instrument [ Time Frame: Measured immediately post-treatment and at Months 6, 12, and 18 follow-ups ]
- Score on the Conflict Behavior Questionnaire [ Time Frame: Measured immediately post-treatment and at Months 6, 12, and 18 follow-ups ]
- Score on the Social Adjustment Scale [ Time Frame: Measured immediately post-treatment and at Months 6, 12, and 18 follow-ups ]
- Score on the Perceived Social Support scale [ Time Frame: Measured immediately post-treatment and at Months 6, 12, and 18 follow-ups ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00258752
|United States, New Jersey|
|Piscataway, New Jersey, United States, 08554|
|United States, New York|
|New York State Psychiatric Institute|
|New York, New York, United States, 10032|
|Principal Investigator:||Jami F. Young, PhD||Rutgers University|