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Respiratory Mechanics and Pleural Effusion

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00258518
Recruitment Status : Completed
First Posted : November 24, 2005
Last Update Posted : March 8, 2012
Information provided by (Responsible Party):
Davide Chiumello, Policlinico Hospital

Brief Summary:
The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.

Condition or disease Intervention/treatment
Critically Ill Acute Lung Injury ARDS Procedure: mechanical ventilation/CT Scan

Detailed Description:
In ALI/ARDS we evaluated the respiratory mechanics (respiratory system, chest wall and lung elastance) at the bedside while pleural effusion was evaluated with CT scan. Thus we will be able to estimate any possible role of pleural effusion on the respiratory mechanics.

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Study Type : Observational
Actual Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Estimation of Respiratory Mechanics (Respiratory System, Chest Wall and Lung Elastance) and Pleural Effusion at the Bedside With CT Scan.
Study Start Date : November 2005
Actual Primary Completion Date : June 2011
Actual Study Completion Date : June 2011

Group/Cohort Intervention/treatment
ALI/ARDS patients
Procedure: mechanical ventilation/CT Scan
evaluation of pleural effusion and respiratory mechanics, CT scan

Primary Outcome Measures :
  1. Role of pleural effusion and respiratory mechanics [ Time Frame: 1 hour ]

Information from the National Library of Medicine

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Ages Eligible for Study:   16 Years to 90 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
ALI/ARDS patients

Inclusion Criteria:

  • ALI/ARDS patients underwent invasive mechanical ventilation

Exclusion Criteria:

  • Haemodynamic instability
  • Chronic obstructive pulmonary disease (COPD) patients

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00258518

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Policlinico Hospital
Milano, Italy, 20122
Sponsors and Collaborators
Policlinico Hospital
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Principal Investigator: Davide Chiumello, MD Policlinico Hospital

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Responsible Party: Davide Chiumello, MD, Policlinico Hospital Identifier: NCT00258518    
Other Study ID Numbers: 1500
First Posted: November 24, 2005    Key Record Dates
Last Update Posted: March 8, 2012
Last Verified: March 2012
Keywords provided by Davide Chiumello, Policlinico Hospital:
Critically ill patients
Additional relevant MeSH terms:
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Lung Injury
Pleural Effusion
Acute Lung Injury
Respiratory Distress Syndrome, Adult
Critical Illness
Disease Attributes
Pathologic Processes
Lung Diseases
Respiratory Tract Diseases
Thoracic Injuries
Wounds and Injuries
Pleural Diseases
Respiration Disorders