Improving Outcomes and Quality of Life After CABG
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|ClinicalTrials.gov Identifier: NCT00256620|
Recruitment Status : Completed
First Posted : November 21, 2005
Last Update Posted : April 3, 2008
|Condition or disease||Intervention/treatment||Phase|
|Coronary Artery Bypass Graft Surgery Patients||Procedure: Mean arterial pressure during cardiopulmonary bypass 80 mmHg vs. customized||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||412 participants|
|Intervention Model:||Factorial Assignment|
|Official Title:||Improving Outcomes and Quality of Life After CABG|
|Study Start Date :||December 1996|
|Study Completion Date :||December 1999|
- Quality of life
- Cardiac morbidity
- Neurologic morbidity
- Neurocognitive deterioration
- • To evaluate the prognostic importance of severe atheromatous disease of the descending aorta as found on transesophageal echocardiography (TEE) as a predictor of neurologic events.
- • To correlate TEE and epiaortic scanning for aortic atheroma with transthoracic echocardiography (TTE) in order to develop a non-invasive screening tool.
- • To assess the clinical significance of persistent post-operative depression as measured by the CES-D by using a structured clinical interview and to evaluate the relationship between pre-operative depression and the occurrence of cardiac, neurologic a
- • To provide data on the mechanism of perioperative neurologic and cognitive complications in order to design other specific intervention to reduce postoperative morbidity.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00256620
|United States, New York|
|New York Presbyterian Hospital-Weill Medical Center|
|New York, New York, United States, 10021|
|Principal Investigator:||Mary E Charlson, MD||Weill Medical College of Cornell University|
|Principal Investigator:||Karl Krieger, MD||Weill Medical College of Cornell University|