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Behavioural Treatment of Hypertension

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT00247910
Recruitment Status : Completed
First Posted : November 2, 2005
Last Update Posted : September 19, 2011
Sponsor:
Collaborator:
Canadian Institutes of Health Research (CIHR)
Information provided by:
University of British Columbia

Brief Summary:
The objective of the study is to determine whether psychological therapy (self-help or individualized intense stress management) is different than a single drug treatment in terms of their effectiveness for lowering blood pressure.

Condition or disease Intervention/treatment Phase
Hypertension Drug: Hydrochlorothiazide Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 150 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Behavioural Treatment of Hypertension
Study Start Date : October 2001
Actual Primary Completion Date : June 2006
Actual Study Completion Date : June 2006

Resource links provided by the National Library of Medicine



Intervention Details:
  • Drug: Hydrochlorothiazide
    Not recorded in detailed description.


Primary Outcome Measures :
  1. Day time ambulatory BP [ Time Frame: See description ]

Secondary Outcome Measures :
  1. 24 hour ambulatory BP, and office resting BP [ Time Frame: See description ]


Information from the National Library of Medicine

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Ages Eligible for Study:   19 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • must be at least 19 years of age
  • subjects can be male or female
  • subjects must have an average resting blood pressure of >140 systolic pressure an/ or >90 diastolic pressure off anti-hypertensive medication

Exclusion Criteria:

  • must not be on more than 2 blood pressure lowering drugs
  • must not have known or suspected of having secondary hypertension on initial examination
  • must not be pregnant or anticipating pregnancy during study period
  • must not have history of allergy, hypersensitivity or intolerance to diuretics
  • must not have medical condition that may result in an unacceptable risk of complications due to uncontrolled hypertension during time period of study
  • must not have average resting BP readings that exceed 190 systolic, or 115 diastolic, or have two consecutive readings of 180 systolic or 110 diastolic

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00247910


Locations
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Canada, British Columbia
UBC Hospital
Vancouver, British Columbia, Canada, V6T 2B5
Sponsors and Collaborators
University of British Columbia
Canadian Institutes of Health Research (CIHR)
Investigators
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Principal Investigator: Wolfgang Linden, PhD University of British Columbia

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Responsible Party: Dr. Wolfgang Linden, University of British Columbia
ClinicalTrials.gov Identifier: NCT00247910    
Other Study ID Numbers: C01-0175
First Posted: November 2, 2005    Key Record Dates
Last Update Posted: September 19, 2011
Last Verified: September 2011
Keywords provided by University of British Columbia:
hypertension, ambulatory BP, office resting BP, hydrochlorothiazide, stress reduction, self-help, psychotherapy, efficacy
Additional relevant MeSH terms:
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Hypertension
Vascular Diseases
Cardiovascular Diseases
Hydrochlorothiazide
Antihypertensive Agents
Diuretics
Natriuretic Agents
Physiological Effects of Drugs
Sodium Chloride Symporter Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action