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Meditation and Hypnosis for Chronic Depressed Mood

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00226863
Recruitment Status : Completed
First Posted : September 27, 2005
Last Update Posted : September 27, 2005
Information provided by:
Stanford University

Brief Summary:
This study examined whether meditation or group psychotherapy including hypnosis plus education, compared to an educational control, would ameliorate long-term depressed mood.

Condition or disease Intervention/treatment Phase
Long Term Depressed Mood Behavioral: meditation plus education Behavioral: group psychotherapy with hypnosis plus education Behavioral: education Phase 3

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Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment

Resource links provided by the National Library of Medicine

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • Currently meeting DSM-IV criteria for a chronic depressive disorder, with the requirement that depressive symptoms had to have lasted for at least 2 years without a remission of 2 months or more.
  • Being 18 years of age or older.
  • Being sufficiently proficient in English to be able to participate in group therapy.
  • Being able to attend weekly meetings at Stanford.

Exclusion Criteria:

  • Concurrent bipolar disorder or severe depressive disorder (this latter was determined in supervision for the SCID interviews).
  • Presence or history of psychosis.
  • A current primary diagnosis of panic disorder, generalized anxiety disorder, or PTSD.
  • A current primary diagnosis of drug or alcohol dependency or abuse (within the last 3 months).
  • Serious suicidal risk, as defined by:
  • Current suicidality, i.e., beyond simple ideation (e.g., making threats or attempts; gathering means; has a plan); OR
  • Serious prior attempts (bodily harm; gathered means; hospitalization).
  • Has a significant medical condition that could interfere with participation in meditation/yoga.
  • Current participation in psychotherapy or a meditation group.
  • Has started (or changed level or type of) prescribed antidepressant medication or St. John's Wort in the previous 3 months.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00226863

Sponsors and Collaborators
Stanford University
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Study Director: Lisa D. Butler, Ph.D. Stanford University
Principal Investigator: David Spiegel, M.D. Stanford University
Layout table for additonal information Identifier: NCT00226863    
Other Study ID Numbers: 1HSA698
First Posted: September 27, 2005    Key Record Dates
Last Update Posted: September 27, 2005
Last Verified: September 2005
Additional relevant MeSH terms:
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Behavioral Symptoms