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Immediate Implant Placement in the Molar Regions

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00226148
Recruitment Status : Completed
First Posted : September 26, 2005
Last Update Posted : September 10, 2009
The Danish Medical Research Council
Information provided by:
University of Aarhus

Brief Summary:

The purpose of this study is to look at the bonehealing when a molar has been extracted and immediately replaced by an implant leaving some defects around the implant.

The defects are being treated in three different with the hypothesis that the three ways of treatment result in equal bonehealing.

Condition or disease Intervention/treatment Phase
Periodontitis Dental Caries Periapical Periodontitis Procedure: Use of a membrane to cover bonedefects around implant Device: Use of bonechips to fill up defects around implant Procedure: Use of membrane and bonechips to manage defects Early Phase 1

Detailed Description:

This study is a randomized clinically controlled study with three group of each thirty patients, where the bonehealing after immediate implantplacement in molarregions is being investigated.

Totally 90 patients are going to get a molar tooth extracted and immediately replaced with an implant (Brånemark System, Wide Platform). The molar tooth should be in such a condition that is has to be extracted.

Extracting a molar leaves a defect which cannot completely be filled out by an implant. The 90 patients are therefore randomised into 3 groups according to how the perimarginal bonedefects around the placed implants are being treated: 1. Bonechips 2. Membrane 3. Bonechips+Membrane. The bonehealing of the defects around the implants are then compared the groups in between. The amount of newly formed bone is being estimated too by digital radiography and subtractionradiography. Furthermore the prognosis for immediate placed implants in molar regions in relation to the method of defectreconstruction one year after crown delivery is also being investigated. All the investigations are conducted with the Ho-hypothesis that there is no difference in the bonehealing the three groups in between.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 92 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Immediate Implant Placement in the Molar Regions
Study Start Date : September 2005
Actual Primary Completion Date : September 2009
Actual Study Completion Date : September 2009

Primary Outcome Measures :
  1. Digitial radiography of the implants at placement, 3 month, 6 month, at abutmentoperation, at crownplacement, 3 month after crownplacement and 6 month after crownplacement. [ Time Frame: see above ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • A molar tooth which has to be extracted
  • Healthy persons with only mild systemic disease with no functional limitation

Exclusion Criteria:

  • Pregnant
  • Any disease that is influencing the turnover of bone or oral mucosa

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00226148

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The Royal Dental College of Aarhus
Aarhus, Denmark, DK-8000
Sponsors and Collaborators
University of Aarhus
The Danish Medical Research Council
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Study Chair: Ann Wenzel, Prof.Dr.Odont, Ph.d.,DDS The Royal Dental College of Aarhus
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Thomas Urban, Dental School, Aarhus University Identifier: NCT00226148    
Other Study ID Numbers: 2005/0091
First Posted: September 26, 2005    Key Record Dates
Last Update Posted: September 10, 2009
Last Verified: September 2009
Keywords provided by University of Aarhus:
Immediate placement
Molar tooth
Additional relevant MeSH terms:
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Dental Caries
Periapical Periodontitis
Periodontal Diseases
Mouth Diseases
Stomatognathic Diseases
Tooth Demineralization
Tooth Diseases
Periapical Diseases
Jaw Diseases