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Efficacy of Cortex Stimulation in Neuropathic Pain

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ClinicalTrials.gov Identifier: NCT00224666
Recruitment Status : Terminated
First Posted : September 23, 2005
Last Update Posted : January 11, 2007
Sponsor:
Information provided by:
Assistance Publique - Hôpitaux de Paris

Brief Summary:

The pains chronic neurogeneses remain difficult to treat whatever are their origin and their localization. The pharmacological therapeutic arsenal answers only partially the symptomatology often very invalidating which these chronic painful patients present. Electric stimulations of the central nervous system currently validated, in particular of the posterior cords of marrow made a significant improvement in a certain number of indications. Nevertheless, considerable patients are not relieved significantly, in particular those presenting of the pains neurogeneses of central origin (syndromes thalamic for example). It is within this framework that recently the stimulation of the sensorimotor cortex developed.

Principal objective: evaluation of the technique of stimulation under cortical on neuropathic pains .


Condition or disease Intervention/treatment Phase
Rebel Neuropathic Pains Device: Cortex stimulation Phase 2

Detailed Description:
The pains chronic neurogeneses remain difficult to treat whatever are their origin and their localization. The pharmacological therapeutic arsenal answers only partially the symptomatology often very invalidating which these chronic painful patients present. Electric stimulations of the central nervous system currently validated, in particular of the posterior cords of marrow made a significant improvement in a certain number of indications. Nevertheless, considerable patients are not relieved significantly, in particular those presenting of the pains neurogeneses of central origin (syndromes thalamic for example). It is within this framework that recently the stimulation of the sensorimotor cortex developed.

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Study Type : Interventional  (Clinical Trial)
Enrollment : 16 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Evaluation of the Effectiveness of Stimulation Cortex Sensorimotor for the Treatment of Rebel Neuropathic Pains
Study Start Date : March 2001
Study Completion Date : November 2005



Primary Outcome Measures :
  1. Efficacy of 50% of EVS at 3 weeks

Secondary Outcome Measures :
  1. Efficacy of 50% of EVS at 6 months and 12 months


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Neurofibromatosis,
  • Rebel chronic neuropathic pain with duration > 1 year and AVS > = 4

Exclusion Criteria:

  • Cancer
  • Epilepsy
  • Cognitive deterioration

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00224666


Locations
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France
Hopital Henri Mondor
Creteil, France, 94000
Sponsors and Collaborators
Assistance Publique - Hôpitaux de Paris
Investigators
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Principal Investigator: N'GUYEN, Pr,MD,PhD Assistance Publique - Hôpitaux de Paris

Publications:
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ClinicalTrials.gov Identifier: NCT00224666    
Other Study ID Numbers: P000901
AOM98134
First Posted: September 23, 2005    Key Record Dates
Last Update Posted: January 11, 2007
Last Verified: January 2007
Keywords provided by Assistance Publique - Hôpitaux de Paris:
Cortex stimulation ,Rebel neuropathic pains
Additional relevant MeSH terms:
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Neuralgia
Peripheral Nervous System Diseases
Neuromuscular Diseases
Nervous System Diseases
Pain
Neurologic Manifestations
Signs and Symptoms