Treatment of Age-Related Macular Degeneration With Anecortave Acetate
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The purpose of this study is to provide compassionate use of anecortave acetate sterile suspension of 15 mg for a series of five patients as a means to control classic neovascularization following failure of treatment with photodynamic therapy using Visudyne.
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Layout table for eligibility information
Ages Eligible for Study:
50 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Clinical diagnosis of patients that previously had a failure of treatment with photodynamic therapy using Visudyne.
Patients must be at least 50 years of age.
Visual acuity of 20/30 to 20/320 in study eye on the Early Treatment of Diabetic Retinopathy Study (ETDRS) visual acuity chart
Visual acuity of 20/800 or better in fellow eye on the ETDRS visual acuity chart
Patient with significantly compromised visual acuity in the study eye due to concomitant ocular conditions.
Patients who have undergone intraocular surgery within the last 2 months.
Patient participating in any other investigational drug study.
Use of an investigational drug or treatment related or unrelated to their condition within 30 days prior to receipt of study medication.
Inability to obtain photographs to document choroidal neovascularization (CNV) (including difficulty with venous access).
Patient with significant liver disease or uremia.
Patient with known adverse reaction to fluorescein and indocyanine green or iodine.
Patient has a history of any medical condition which would preclude scheduled visits or completion of study
Patient has had insertion of scleral buckle in the study eye
Patient has received radiation treatment
Patient is on anticoagulant therapy with the exception of aspirin