Intraoperative Nitrous Oxide and Postoperative Pain for Patients With Current Opioid Treatment (PROTOX)
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ClinicalTrials.gov Identifier: NCT00210158 |
Recruitment Status :
Completed
First Posted : September 21, 2005
Last Update Posted : July 26, 2013
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Chronic Pain | Procedure: Nitrous oxyde | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 36 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double |
Primary Purpose: | Treatment |
Official Title: | Effects of Intraoperative Nitrous Oxide on Postoperative Pain for Patients With Current Opioid Treatment After Vertebroplasty. |
Study Start Date : | January 2005 |
Actual Study Completion Date : | December 2006 |

- Visual Analogue Scale (VAS) and morphine consumption recorded for 48 postoperative hours (every 8 hours).
- Preoperative and postoperative pressure pain threshold (pressure algometer)

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Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion criteria:
> 18 years old Current opioid treatment > 1 month patients scheduled to undergo vertebroplasty with general anesthesia

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00210158
France | |
Institut Bergonié - Centre Régional de Luttre Contre le Cancer DE Bordeaux et du Sud Ouest | |
Bordeaux, France, 33076 |
Principal Investigator: | Fabrice LAKDJA, MD | Institut Bergonié - Centre Régional de Luttre Contre le Cancer de Bordeaux et du Sud Ouest |
ClinicalTrials.gov Identifier: | NCT00210158 History of Changes |
Other Study ID Numbers: |
IB2005-05 PROTOX |
First Posted: | September 21, 2005 Key Record Dates |
Last Update Posted: | July 26, 2013 |
Last Verified: | October 2007 |
Keywords provided by Institut Bergonié:
Current opioid treatment Nitrous oxide Chronic pain |
Opioid therapy Postoperative hyperalgesia Acute opioid tolerance |
Additional relevant MeSH terms:
Pain, Postoperative Chronic Pain Pain Neurologic Manifestations Nervous System Diseases Postoperative Complications Pathologic Processes Signs and Symptoms Analgesics, Opioid Nitrous Oxide |
Narcotics Central Nervous System Depressants Physiological Effects of Drugs Analgesics Sensory System Agents Peripheral Nervous System Agents Anesthetics, Inhalation Anesthetics, General Anesthetics Analgesics, Non-Narcotic |