Acute, Affective, Organic Disorders.
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00201474|
Recruitment Status : Completed
First Posted : September 20, 2005
Last Update Posted : August 4, 2016
|Condition or disease|
A limited number of patients admitted to psychiatric acute wards or Psychiatric Intensive Care Units are admitted with a fluctuating array of psychiatric symptoms including brief depressive episodes. These patients do not fit into the present diagnostic systems due to short duration of affective symptoms and the fluctuating arrays of other symptoms. Case histories indicate that these patients have psychiatric conditions due to epilepsy or organic brain dysfunctions.
In the study acutely admitted patients filling criteria for two recent DSM-4 axis 1 diagnoses (one is a brief depressive period) during the last two weeks are compared to age- and sex-matched patients acutely admitted with a major depressive disorder. The patients are rated with a number of rating scales at admittance, day 5, after two weeks and three months. EEG and QEEG are taken three times the first week. MRI, drug screening and blood screening of medication-concentrations are taken.
|Study Type :||Observational|
|Actual Enrollment :||32 participants|
|Official Title:||Signs of Organic Brain Dysfunction in Psychiatric Patients With Fluctuating Psychiatric Symptoms Including Brief Depressions Compared to Patients With a Major Depressive Episode.|
|Study Start Date :||October 1998|
|Actual Primary Completion Date :||October 2004|
|Actual Study Completion Date :||June 2010|
brief depressive periods
brief depressive periods together with other fluctuating psychiatric symptoms
|major depressive disorder|
- epilepsy or an other organic brain disorder [ Time Frame: 1 week ]EEG and QEEG are taken three times in the first week
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00201474
|Østmarka Psychiatric Department, St. Olavs Hospital|
|Trondheim, Norway, 7441|
|Study Chair:||Olav M Linaker, Professor||Norwegian University of Science and Technology|