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Effects of Local Anesthetic or Saline Solution on Peripheral Nerve Stimulation – a Randomised Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00176111
Recruitment Status : Terminated
First Posted : September 15, 2005
Last Update Posted : November 17, 2005
Rechbergklinik Bretten
Information provided by:
Heidelberg University

Brief Summary:
In this study we want to examine the effect of a small amount of local anesthetic or saline solution on nerve conduction using a peripheral nerve stimulator.

Condition or disease Intervention/treatment Phase
Percutaneous Electric Nerve Stimulation Procedure: peripheral nerve stimulation (procedure) Phase 4

Detailed Description:

Using electrical nerve stimulation in performing peripheral nerve helps to control the needle position in relation to the nerve and therefore may increase the likelihood of a successful nerve block. Defining the minimal stimulating current accepted also may help to avoid direct contact between nerve and needle or accidental endoneural injection and subsequent nerve lesion.

In recent years there have been many reports where several nerves, parts thereof or plexuses have been anesthetised using a multiple injection approach. That is, nerves in close proximity of each other have been subsequently blocked after using a nerve stimulator to locate them.

It is not clear though, whether a nerve may already be partially anesthetised in this situation and whether that would impair the correct use of a peripheral nerve stimulator.

The aim of this study is to examine the excitability of a peripheral nerve after injecting a small amount of local anesthetic agent or saline solution into the proximity of the nerve.

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Study Type : Interventional  (Clinical Trial)
Enrollment : 40 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Effects of Local Anesthetic or Saline Solution on Peripheral Nerve Stimulation – a Randomised, Double-Blind, Multicenter Study About the Stimulability of Anesthetized Nerves
Study Start Date : January 2004
Study Completion Date : January 2005

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

ASA 1-2

Exclusion Criteria:

peripheral neuropathy, ASA >2

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00176111

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Bretten, Baden Wuerttemberg, Germany, 75015
Sponsors and Collaborators
Heidelberg University
Rechbergklinik Bretten
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Study Chair: Heinz Kaiser, MD Rechbergklinik Bretten
Publications of Results:
Layout table for additonal information Identifier: NCT00176111    
Other Study ID Numbers: nervstim001
First Posted: September 15, 2005    Key Record Dates
Last Update Posted: November 17, 2005
Last Verified: January 2004
Keywords provided by Heidelberg University:
peripheral nerve stimulation
local anesthestics
regional anesthestia
nerve damage