Enteral Nutrition in Liver Cirrhosis
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|ClinicalTrials.gov Identifier: NCT00168961|
Recruitment Status : Completed
First Posted : September 15, 2005
Last Update Posted : May 7, 2010
Malnutrition is frequently occurring in patients with liver cirrhosis and is associated with a poorer outcome, as it determines life quality and affects both morbidity and mortality.
Long term prognosis after liver transplantation also depends on the nutritional status.
Therefore, the early diagnosis and intervention for malnutrition is an important issue in the clinical management of liver cirrhosis. However, oral intake has been shown to be insufficient due to disease related anorexia or concomitant drowsiness and confusion.
Specific aims: To investigate the effect of early nutritional intervention via tube feeding on nutritional status, functional status (hand grip strength and peak flow), life quality and disease related complications such as intestinal permeability, and oxidative stress, as well as liver function.
|Condition or disease||Intervention/treatment||Phase|
|Liver Cirrhosis||Dietary Supplement: High Protein Energy, Fresenius-Kabi (nutritional intervention)||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||December 2003|
|Actual Primary Completion Date :||December 2006|
|Actual Study Completion Date :||June 2007|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00168961
|Charite Universitätsmedizin Klinik für Gastroenterologie|
|Berlin, Germany, 10117|
|Principal Investigator:||Matthias Pirlich, MD||Charite Universitätsmedizin CCM Klinik für Gastroenterologie|