Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure
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The purpose of this study is to compare the side effects of radiation treatment and surgery versus radiation alone, where no surgery is done to move the salivary gland and place it under the chin region where it can be shielded from radiation.
Condition or disease
Head and Neck Cancer
Procedure: radiation treatment and surgeryProcedure: radiation alone
To Evaluate the Effects of Transfer of Submandibular Salivary Gland to the Submental Region (Outside the Radiation Field) on Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure
Study Start Date :
Actual Primary Completion Date :
Actual Study Completion Date :
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Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients with a histological diagnosis of squamous cell carcinoma
Patients with unilateral or no neck involvement of the nasopharynx
The submandibular transfer will be done on the uninvolved side of the neck.
Karnofsky score greater than or equal to 70
Expected survival greater than one year
A signed informed consent
Bilateral neck nodes involvement. Involvement of level 1 lymph nodes on the side of the proposed procedure.