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Ventricular Synchrony in Pediatric Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00165932
Recruitment Status : Completed
First Posted : September 14, 2005
Last Update Posted : June 1, 2012
Children's Healthcare of Atlanta
Information provided by (Responsible Party):
Patricio A. Frias, MD, Emory University

Brief Summary:

At Children's Healthcare of Atlanta, children who have irregular heart rhythms are often referred for evaluation. Sometimes they also need a procedure to correct their irregular heart rhythm. An echocardiogram is routinely used as part of their evaluation and follow-up. The echocardiogram including Tissue Doppler Imaging (TDI) works by bouncing sound waves off the heart similar to radar. A new echocardiogram technology, Tissue Synchronization Imaging (TSI), should help doctors look at heart function compared to heart rhythm. All three of these are noninvasive, which means they work from a probe outside the body and are not painful.

The purpose of this study is to see how Tissue Synchronization Imaging works in patients with heart rhythm problems. We will use patients who have a heart irregularity. We will also look at children and young adults with normal heart function to establish normal values for TSI.

All pediatric patients we approach for this study will receive an echocardiogram recommended by their cardiologist (standard of care), plus TSI, a new part of a heart ultrasound The young adult population will undergo a heart ultrasound plus TSI. This young adult population will be selected from medical students at Emory University. During the consent process, the medical students will be informed that participation is voluntary and if they decide not to participate, it will not affect their grades, etc.

Condition or disease
Irregular Heart Rate

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Study Type : Observational
Actual Enrollment : 145 participants
Observational Model: Case-Control
Time Perspective: Prospective
Official Title: A Single Center Prospective, Pilot Study Examining the Non-invasive Evaluation of Ventricular Synchrony in Pediatric Patients
Study Start Date : June 2004
Actual Primary Completion Date : December 2009
Actual Study Completion Date : December 2009

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
We are currently only enrolling those patients with the diagnosis of SVT who are scheduled for an electrophysical study at Children's Healthcare of Atlanta Egleston Campus.

Inclusion Criteria:

Any pediatric patient already referred for EPS and possible RFA at Children's Healthcare of Atlanta for the following diagnoses:

  • Non-preexcited supraventricular tachycardia
  • Atrioventricular Node Reentrant Tachycardia (AVNRT)
  • Atrioventricular Reentry Tachycardia (AVRT) utilizing a concealed AC
  • Atrial Flutter
  • Wolff-Parkinson-White syndrome (WPW)
  • Ventricular tachycardia with structurally normal hearts with normal function We will also be enrolling young adult subjects who will be recruited for participation. -

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00165932

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United States, Georgia
Children's Healthcare of Atlanta at Egleston
Atlanta, Georgia, United States, 30322
Sponsors and Collaborators
Emory University
Children's Healthcare of Atlanta
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Principal Investigator: Patricio Frias, MD Emory University
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Responsible Party: Patricio A. Frias, MD, Associate Professor, Emory University Identifier: NCT00165932    
Other Study ID Numbers: 417-2004
First Posted: September 14, 2005    Key Record Dates
Last Update Posted: June 1, 2012
Last Verified: May 2012
Keywords provided by Patricio A. Frias, MD, Emory University: