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Evaluating a Collaborative Care Model for the Treatment of Schizophrenia (EQUIP)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00119574
Recruitment Status : Completed
First Posted : July 13, 2005
Last Update Posted : April 7, 2015
University of California, Los Angeles
Information provided by (Responsible Party):
VA Office of Research and Development ( US Department of Veterans Affairs )

Brief Summary:

Policy makers and consumers are increasingly concerned about the quality and efficiency of care provided to individuals with severe, chronic illnesses such as schizophrenia. These illnesses are expensive to treat and present significant challenges to organizations that are responsible for providing effective care. Occurring in 1% of the United States population, schizophrenia accounts for 10% of permanently disabled people, and 2.5% of all healthcare expenditures. Clinical practice guidelines have been promulgated. Schizophrenia is treatable and outcomes can be substantially improved with the appropriate use of antipsychotic medication, caregiver education and counseling, vocational rehabilitation, and assertive treatment. However, in the VA and other mental health systems, many patients with schizophrenia receive substandard care. Methods are needed that improve the quality of usual care for this disorder while being feasible to implement at typical clinics.

To date, most efforts to improve care for schizophrenia have focused on educating clinicians or changing the financing of care, and have had limited success. We believe a more fundamental approach should be tried. While there are many potential strategies, experience in chronic medical illness and mental health support the efficacy of specific approaches. Collaborative care models are one such approach. They are a blueprint for reorganizing practice, and involve changes in division of labor and responsibility, adoption of new care protocols, and increased attention to patients' needs. Although collaborative care models have been successful in other chronic medical conditions, they have not yet been studied in the treatment of schizophrenia.

We have developed a collaborative care model for schizophrenia that builds on work in other disorders, and includes service delivery approaches that are known to be effective in schizophrenia. The model focuses on improving treatment through assertive care management, caregiver education and support, and standardized patient assessment with feedback of information to psychiatrists. This project, "EQUIP" (Enhancing Quality Utilization In Psychosis) is implementing collaborative care and evaluating its effectiveness in schizophrenia.

Condition or disease Intervention/treatment Phase
Schizophrenia Disorders Chronic Illness Schizoaffective Disorder Weight Gain Procedure: Collaborative Chronic Illness Model Not Applicable

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 443 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Evaluating a Collaborative Care Model for the Treatment of Schizophrenia (EQUIP)
Study Start Date : January 2002
Actual Study Completion Date : December 2004

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Schizophrenia

Arm Intervention/treatment
Arm 1 Procedure: Collaborative Chronic Illness Model

Primary Outcome Measures :
  1. At 15 mo.: Provider attitudes on controlling symptoms & side-effects, & on family involvement Patient clinical outcomes Throughout the study: Patient compliance Provider practice patterns & adherence to VA guidelines Patient utilization

Secondary Outcome Measures :
  1. Process assessment throughout the course of the study of barriers and facilitators to the intervention�s implementation

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

Providers (Psychiatrists, Case Managers, Nurses):

Working at one of the participating VA Mental Health Clinics

Providers: 68 Patients: 375


  • At least 18 years old
  • Diagnosis of Schizophrenia, Schizoaffective, or schizophreniform disorder
  • At least 2 treatment visits with a psychiatrist at the clinic during the previous 6 months.

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00119574

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United States, California
VA Greater Los Angeles Healthcare System, West Los Angeles, CA
West Los Angeles, California, United States, 90073
Sponsors and Collaborators
US Department of Veterans Affairs
University of California, Los Angeles
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Principal Investigator: Alexander Stehle Young, MD MSHS VA Greater Los Angeles Healthcare System, West Los Angeles, CA
Additional Information:
Publications of Results:
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Responsible Party: US Department of Veterans Affairs Identifier: NCT00119574    
Other Study ID Numbers: CPI 99-383
RCD 00-033
NIMH MH-5423
NIMH MH-068639
First Posted: July 13, 2005    Key Record Dates
Last Update Posted: April 7, 2015
Last Verified: July 2005
Keywords provided by VA Office of Research and Development ( US Department of Veterans Affairs ):
Randomized Controlled Trial
Quality of Health Care
Health Services Research
Medical Informatics Computing
Services, Mental Health
Medicine, Evidence-Based
Quality Assurance, Healthcare
Quality Indicators, Health Care
Additional relevant MeSH terms:
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Weight Gain
Chronic Disease
Psychotic Disorders
Pathologic Processes
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders
Body Weight Changes
Body Weight
Disease Attributes