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Meaning-Centered Psychotherapy in Advanced Cancer

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00067288
Recruitment Status : Completed
First Posted : August 15, 2003
Last Update Posted : August 18, 2006
Information provided by:
National Center for Complementary and Integrative Health (NCCIH)

Brief Summary:
We have developed an 8-week Meaning-Centered Group Psychotherapy designed to help patients with advanced cancer sustain or enhance a sense of meaning, peace and purpose despite the limitations of their cancer illness. This project's overall aim is to explore the feasibility and efficacy of this new and unique psychotherapy intervention for advanced cancer patients in enhancing psychological and spiritual well-being and quality of life by comparing it with a standard supportive group psychotherapy.

Condition or disease Intervention/treatment Phase
Lymphoma, Non-Hodgkin Neoplasms Behavioral: Meaning-Centered Group Psychotherapy Behavioral: Standard Supportive Group Psychotherapy Phase 2

Detailed Description:
As per Brief Summary

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Study Type : Interventional  (Clinical Trial)
Enrollment : 118 participants
Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Educational/Counseling/Training
Official Title: Meaning-Centered Psychotherapy in Advanced Cancer
Study Start Date : May 2002
Study Completion Date : March 2006

Resource links provided by the National Library of Medicine

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 21 years of age or older;
  • English speaking;
  • Stage III or IV solid-tumor or Non-Hodgkin's Lymphoma;
  • Receiving ambulatory care at Memorial Sloan-Kettering Cancer Center in New York City;

Exclusion Criteria:

  • Significant psychiatric disturbance sufficient, in the investigator's judgment, to preclude participation in a group-format intervention;
  • Presence of cognitive impairment disorder, such as delirium or dementia that is sufficient, in the investigator's opinion, to preclude meaningful participation and/or informed consent;
  • Karnofsky Performance Rating Scale below 50 or physical limitations or illness severity sufficient to preclude participation in outpatient group psychotherapy.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00067288

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United States, New York
Memorial Sloan-Kettering Institute for Cancer Research
New York, New York, United States, 10021
Sponsors and Collaborators
National Center for Complementary and Integrative Health (NCCIH)
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Principal Investigator: William Breitbart, MD Memorial Sloan Kettering Cancer Center
OverallOfficial: Christopher Gibson, PhD Project Coordinator Memorial Sloan-Kettering Cancer Center
Layout table for additonal information Identifier: NCT00067288    
Other Study ID Numbers: R21AT001031-01 ( U.S. NIH Grant/Contract )
First Posted: August 15, 2003    Key Record Dates
Last Update Posted: August 18, 2006
Last Verified: August 2006
Keywords provided by National Center for Complementary and Integrative Health (NCCIH):
Stage 3 cancer;
Stage 4 cancer;
solid tumor cancer;
Non-Hodgkin's Lymphoma;
solid tumors;
end-stage cancer;
group psychotherapy;
emotional support;
support groups
Additional relevant MeSH terms:
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Lymphoma, Non-Hodgkin
Neoplasms by Histologic Type
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases