Assessment of Potential Interactions Between Cocaine and Tolcapone - 1
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ClinicalTrials.gov Identifier: NCT00033059
Recruitment Status : Unknown
Verified August 2003 by National Institute on Drug Abuse (NIDA). Recruitment status was: Active, not recruiting
The purpose of this study is to assess the potential interactions between intravenous (IV) cocaine and tolcapone.
Condition or disease
Double-blind, inpatient study by screening responses to cocaine infusions of 20 and 40 mg i.v. subjects into 1 of 2 treatment groups to assess potential interactions between i.v. cocaine infusion and treatment with tolcapone.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 45 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Volunteers dependent on cocaine and are non-treatment seeking; between 18-45 yrs of age; DSM-4 criteria for cocaine abuse or dependence
Additional criteria available during screening at the site