Study of Taste Deficits
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|ClinicalTrials.gov Identifier: NCT00022997|
Recruitment Status : Completed
First Posted : August 20, 2001
Last Update Posted : June 6, 2019
This study will explore the genetics of taste and taste deficits. The sense of taste plays a crucial role in food choices, allowing people to identify beneficial foods (those with high caloric value, which are typically sweet) and foods likely to be toxic (usually bitter substances). The loss of sense of taste in older people plays a role in decreased appetite and poor nutrition. Taste deficits may adversely affect people in ways that are not well understood. This study will examine why some people (about one-fourth of all people in the United States) cannot taste a substance called phenylthiocarbamide (PTC). The inability to taste PTC is due to inherited factors that are not yet clear.
Individuals age 18 and older who can taste PTC and individuals who cannot taste PTC may be eligible for this study. Participants will taste a number of liquid solutions until they find one with a clear taste. Then they will taste another group of solutions and decide which ones have that taste and which have no taste. Finally, they will taste a third group of solutions until they find one with a different taste. About 2 tablespoons of blood will be drawn from participants for genetic tests related to the sense of taste.
|Condition or disease|
|Taste Disorder Healthy|
|Study Type :||Observational|
|Actual Enrollment :||450 participants|
|Official Title:||Studies of Deficits in the Sense of Taste|
|Study Start Date :||August 16, 2001|
|Study Completion Date :||June 4, 2019|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00022997
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike|
|Bethesda, Maryland, United States, 20892|
|Principal Investigator:||Dennis T Drayna, Ph.D.||National Institute on Deafness and Other Communication Disorders (NIDCD)|