Porfimer Sodium in Diagnosing Patients With Head and Neck Cancer
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|ClinicalTrials.gov Identifier: NCT00002964|
Recruitment Status : Completed
First Posted : April 27, 2004
Last Update Posted : February 5, 2013
RATIONALE: Drugs that make cancer cells more visible to light may help in the diagnosis of head and neck cancer.
PURPOSE: Phase II trial to study the usefulness of porfimer sodium in diagnosing patients with head and neck cancer.
|Condition or disease||Intervention/treatment||Phase|
|Head and Neck Cancer||Drug: porfimer sodium Other: fluorophotometry||Phase 2|
OBJECTIVES: I. Determine whether porfimer sodium fluorescence can be used to reveal early malignant changes in patients with lesions of the oral cavity. II. Investigate whether porfimer sodium fluorescence can define areas of field cancerization in the oral mucosa, specifically satellite foci of malignant cells within the margins of an excision. III. Determine whether uptake of fluorescence is indicative of disease stage.
OUTLINE: Patients receive porfimer sodium IV bolus and are kept in subdued light until examination with a fluorescence photometer 48 hours later. Patients must avoid sunlight and other intense lights for an additional 30 days.
PROJECTED ACCRUAL: 20 patients will be accrued per year.
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||Pilot Study for the Diagnosis of Head and Neck Cancer: Photofrin and Visible Light|
|Study Start Date :||February 1995|
|Actual Primary Completion Date :||April 2004|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00002964
|United States, New York|
|Roswell Park Cancer Institute|
|Buffalo, New York, United States, 14263-0001|
|Study Chair:||Wesley L. Hicks, MD||Roswell Park Cancer Institute|