A Compassionate Use Study of Tenofovir Disoproxil Fumarate as Treatment for HIV Infection
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
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This study allows patients who need a new anti-HIV treatment to take tenofovir disoproxil fumarate (tenofovir DF), an experimental drug. This study also looks at any side effects the drug causes.
Condition or disease
Drug: Tenofovir disoproxil fumarate
HIV-1-infected patients who are currently receiving stable antiretroviral therapy add tenofovir DF to their regimen. Study participation lasts for approximately 48 weeks. Interested patients should contact their physicians.
An Open-Label, Multicenter, Compassionate Access Study of the Safety of Tenofovir Disoproxil Fumarate Administered in Combination With Other Antiretroviral Agents for the Treatment of HIV-1 Infected Patients
Study Start Date :
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Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
You may be eligible for this study if you:
Have a viral load greater than or equal to 10,000 copies/ml.
Have a CD4 count less than or equal to 50 cells/mm3, or have a CD4 count greater than 50 and no more than 200 cells/mm3 with an opportunistic (AIDS-related) infection within 90 days of study entry. (Patients with a CD4 count above 200 cells/mm3 may be considered depending on drug supply.)
Are at least 18 years old.
Agree to use barrier methods of birth control (such as condoms) while on the study and for 30 days afterward.
Have a life expectancy of at least one year.
You will not be eligible for this study if you:
Have a history of a serious kidney or bone disease.
Have severe nausea, vomiting, or trouble taking medications by mouth.
Are pregnant or breast-feeding.
Abuse alcohol or other substances that your doctor thinks would interfere with taking this medicine.
Are taking any medicines that interfere with kidney functions.