Racial Differences in Control of Blood Vessel Tone and Blood Flow
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|ClinicalTrials.gov Identifier: NCT00001747|
Recruitment Status : Completed
First Posted : December 10, 2002
Last Update Posted : March 4, 2008
Black Americans tend to die more often from and have more diseases associated with heart disease than White Americans. The exact cause of this is unknown, but it is likely a combination of genetics, behavior, risk factors, strategies for education and prevention, and socioeconomic factors.
Recent studies have suggested that faster biological processes in blood vessels of Black Americans may be the cause of increased amounts of heart disease. In addition, small blood vessels in Black Americans seem to be less responsive to substances that relax blood vessels, which may explain increased blood pressure levels.
In this study researchers plan to study artery relaxation (dilation) in response substances affecting the cells lining blood vessels (endothelin). Researchers will compare the results of this study in black and white people to find out whether racial differences may contribute to increases in heart disease and heart related deaths in blacks.
|Condition or disease|
|Atherosclerosis Healthy Hypertension|
|Study Type :||Observational|
|Estimated Enrollment :||108 participants|
|Official Title:||Racial Differences in Flow Mediated Vasodilator Function|
|Study Start Date :||May 1998|
|Estimated Study Completion Date :||March 2001|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001747
|United States, Maryland|
|National Heart, Lung and Blood Institute (NHLBI)|
|Bethesda, Maryland, United States, 20892|