Magnetic Resonance Imaging at Different Levels of Magnetic Intensity

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00001619
Recruitment Status : Completed
First Posted : November 4, 1999
Last Update Posted : July 2, 2017
Information provided by:
National Institutes of Health Clinical Center (CC)

Brief Summary:

Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation). MRI uses different levels of magnetic fields to create images of the body and organs. Occasionally, researchers will give patients undergoing a MRI an injection of a substance called gadolinium. Gadolinium works by brightening areas of the magnetic resonance image, thereby improving the contrast.

In this study researchers will use magnetic resonance imaging and contrast substances, like gadolinium, on normal volunteers in order to evaluate different aspects of its performance. Information gathered from this study may be used to develop more specific research studies involving MRI.

Condition or disease
Cardiovascular Disease Healthy

Detailed Description:
Technical evaluation of magnetic resonance imaging and spectroscopy will be performed on normal volunteers. These studies will be conducted in the MRI systems located at the NIH. These studies may involve the intravenous administration of commercially available MR contrast media and exercise. The results will be used to evaluate the performance of various pulse sequences, gradient coils, and RF coils on human subjects and will provide essential ground work for specific patient protocols.

Study Type : Observational
Actual Enrollment : 497 participants
Official Title: Magnetic Resonance at 1.5 and 3 Tesla
Study Start Date : November 5, 1996
Study Completion Date : July 20, 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: MRI Scans

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Any normal volunteer greater than or equal to 18 who is capable of giving informed consent.


A subject will be excluded if he/she has a contraindication to MR scanning such as:

  1. Brain aneurysm clip
  2. Implanted neural stimulator
  3. Implanted cardiac pacemaker or defibrillator
  4. Cochlear or ear implant
  5. Ocular foreign body (e.g. metal shavings)
  6. Insulin pump
  7. Pregnant women (when uncertain, subject will undergo urine or blood testing).
  8. Claustrophobia
  9. Any condition in the Principal Investigator's judgement which present unnecessary risk


  1. Lactating Women
  2. Renal or hepatic disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00001619

United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
Sponsors and Collaborators
National Heart, Lung, and Blood Institute (NHLBI)