The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders
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|ClinicalTrials.gov Identifier: NCT00001232|
Recruitment Status : Completed
First Posted : December 10, 2002
Last Update Posted : March 4, 2008
The normal menstrual cycle is produced by a series of hormonal signals that starts with the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. The hypothalamus is located in the brain and is often referred to as the master gland. GnRH then acts on the pituitary gland and causes it to release two hormones, follicle stimulating hormone (FSH) and lutenizng hormone (LH). LH and FSH act on the ovary and cause it to release the hormones directly involved in menstruation, estrogen and progesterone.
The purpose of this research study is to evaluate the hypothalamic-pituitary-gonadal axis activity as measured by pituitary hormones, FSH and LH in response to intravenous doses of gonadotropin releasing hormone (GnRH) in menstrual cycle-related hormones.
|Condition or disease|
|Depressive Disorder Healthy Mental Disorders Mood Disorders|
|Study Type :||Observational|
|Estimated Enrollment :||140 participants|
|Official Title:||Pituitary Gonadotropin Response to GnRH Stimulation in Menstrual, Climacteric and, Menopause-Related Mood and Behavioral Disorders|
|Study Start Date :||July 1988|
|Estimated Study Completion Date :||June 2000|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001232
|United States, Maryland|
|National Institute of Mental Health (NIMH)|
|Bethesda, Maryland, United States, 20892|