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Neuropsychological Evaluation of Psychiatric and Neurological Patients

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00001192
First Posted: November 4, 1999
Last Update Posted: July 2, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Institutes of Health Clinical Center (CC)
  Purpose

This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries.

The goals of this research study are to;

  1. Create descriptions based on the performance of each patient on the test batteries. Then use this information to relate patient behavior to their neurophysiological, neuroradiological, and biochemical descriptions.
  2. Define subgroups of patients based on their neurobehavior in order to decrease the variability of psychiatric diagnoses, treatments, and prognoses.

Condition
Anxiety Disorder Head Injury Mood Disorder Schizophrenia Seizures

Study Type: Observational
Official Title: Neuropsychological Evaluation of Psychiatric and Neurological Patients

Resource links provided by NLM:


Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment: 4300
Study Start Date: October 18, 1983
Estimated Study Completion Date: December 20, 2006
Detailed Description:
Neuropsychological tests are used to provide an assessment of cognitive functions in patients with idiopathic generalized epileptic (IGE) disorders and their first-degree relatives. The battery comprises tests designed to tap attention, memory, selected sensory and perceptual functions, vigilance, and visual-spatial functions. Modified batteries have been developed for the assessment of children ages 5-8, and children ages 8-16. The data provided by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   up to 95 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria
  • INCLUSION CRITERIA:

Patients.

Normal volunteers.

EXCLUSION CRITERIA:

Subjects over 95 years of age.

Subjects with a history of alcohol or drug abuse, psychopathology, or central nervous system pathology, other than that which defines group membership, may be excluded.

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001192


Locations
United States, District of Columbia
Childrens National Medical Center
Washington, D.C., District of Columbia, United States
United States, Maryland
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
United States, Michigan
Henry Ford Health Systems
Detroit, Michigan, United States, 48202
United States, New York
Mt. Sinai Medical Center
New York, New York, United States, 10029-0574
Columbia University
New York, New York, United States, 10032-3784
France
Genethon
Every Cedex, France
Russian Federation
Mosco Research Institute of Psychiatry
Moscow, Russian Federation
Sponsors and Collaborators
National Institute of Mental Health (NIMH)
  More Information

Publications:
ClinicalTrials.gov Identifier: NCT00001192     History of Changes
Other Study ID Numbers: 830176
83-M-0176
First Submitted: November 3, 1999
First Posted: November 4, 1999
Last Update Posted: July 2, 2017
Last Verified: December 20, 2006

Keywords provided by National Institutes of Health Clinical Center (CC):
Executive Functions
Language
Attention
Visual-Spatial Ability
Memory
Motor Behavior
Intelligence
Personality
Visual and Auditory Functioning
Hand and Eye Dominance
Normal Volunteer
Neuropsychiatric Disorders

Additional relevant MeSH terms:
Disease
Schizophrenia
Seizures
Anxiety Disorders
Mood Disorders
Craniocerebral Trauma
Pathologic Processes
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders
Epilepsy
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms
Trauma, Nervous System
Wounds and Injuries