Combination Chemotherapy in Patients With Zollinger-Ellison Syndrome and Tumors of the Pancreas
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|ClinicalTrials.gov Identifier: NCT00001165|
Recruitment Status : Completed
First Posted : November 4, 1999
Last Update Posted : March 4, 2008
Patients with Zollinger-Ellison Syndrome suffer from ulcers of the upper gastrointestinal tract, higher than normal levels of gastric acid, and tumors of the pancreas known as non-beta islet cell tumors.
Prior to the use of drugs to cure the ulcers, patients typically died due to severe ulcers. Because of such effective drugs to treat the ulcers it is more common to see patients dying due to the pancreatic tumors.
The study will observe patients suffering from Zollinger-Ellison Syndrome and non-beta islet cell tumors and determine the effectiveness of combined chemotherapy with streptozotocin, 5-fluorouracil, and doxorubicin.
|Condition or disease||Intervention/treatment||Phase|
|Islet Cell Adenoma Neoplasm Metastasis Zollinger Ellison Syndrome||Drug: combined chemotherapy with streptozotocin, 5-fluorouracil, and doxorubicin||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||999 participants|
|Official Title:||Evaluation of Chemotherapy With Streptozotocin Combined With 5-Fluorouracil and Adriamycin in Patients With Zollinger-Ellison Syndrome and Metastatic Non-Beta-Islet Cell Neoplasm|
|Study Start Date :||September 1978|
|Estimated Study Completion Date :||August 2003|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00001165
|United States, Maryland|
|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|
|Bethesda, Maryland, United States, 20892|