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Asthma Clinical Research Network (ACRN)

This study has been withdrawn prior to enrollment.
(Record is an ACRN grant summary & not reflective of an individual trial. All ACTs conducted by ACRN were individually registered on the PRS.)
ClinicalTrials.gov Identifier:
First Posted: October 28, 1999
Last Update Posted: January 16, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by:
Milton S. Hershey Medical Center
This study will establish a network of interactive asthma clinical research groups to evaluate current therapies, new therapies, and management strategies for adult asthma.

Condition Intervention Phase
Asthma Lung Diseases Drug: Albuterol Drug: Colchicine Drug: Adrenal Cortex Hormones Drug: Adrenergic-Beta Agonists Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Official Title: Asthma Clinical Research Network (ACRN)

Resource links provided by NLM:

Further study details as provided by Milton S. Hershey Medical Center:

Enrollment: 0
Study Start Date: September 1993
Estimated Study Completion Date: July 2008
  Show Detailed Description


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Patients with asthma; specific eligibility criteria vary for each study.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000577

United States, California
University of California at San Diego
La Jolla, California, United States, 92103
University of California, San Francisco
San Francisco, California, United States, 94143
United States, Colorado
National Jewish Medical & Research Center
Denver, Colorado, United States, 80206
United States, Massachusetts
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
United States, Missouri
Washington University
St. Louis, Missouri, United States, 63110
United States, North Carolina
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States, 27103
United States, Wisconsin
University of Wisconsin at Madison
Madison, Wisconsin, United States, 53792
Sponsors and Collaborators
Milton S. Hershey Medical Center
National Heart, Lung, and Blood Institute (NHLBI)
Study Chair: Homer A. Boushey University of California, San Francisco
Study Chair: William Calhoun University of Pittsburgh at Pittsburgh
Study Chair: Mario Castro Washington University School of Medicine
Study Chair: Vernon Chinchilli Milton S. Hershey Medical Center
Study Chair: Elliot Israel Brigham and Women's Hospital
Study Chair: Robert F. Lemanske, Jr. University of Wisconsin, Madison
Study Chair: Richard J. Martin National Jewish Medical & Research Center
Study Chair: Stephen P. Peters Wake Forest University Health Sciences
Study Chair: Stephen I. Wasserman University of California, San Diego
  More Information

Additional Information:
King TS, Chinchilli VM and the Asthma Clinical Research Network:. Robust estimators of the concordance correlation coefficient. Joint Statistical Meetings, Page 50, August 2001.

ClinicalTrials.gov Identifier: NCT00000577     History of Changes
Other Study ID Numbers: 215
U10HL074204 ( U.S. NIH Grant/Contract )
U10HL051823 ( U.S. NIH Grant/Contract )
U10HL051831 ( U.S. NIH Grant/Contract )
U10HL051834 ( U.S. NIH Grant/Contract )
U10HL051843 ( U.S. NIH Grant/Contract )
U10HL051845 ( U.S. NIH Grant/Contract )
U10HL056443 ( U.S. NIH Grant/Contract )
U10HL074073 ( U.S. NIH Grant/Contract )
U10HL074206 ( U.S. NIH Grant/Contract )
U10HL074208 ( U.S. NIH Grant/Contract )
U10HL074212 ( U.S. NIH Grant/Contract )
U10HL074218 ( U.S. NIH Grant/Contract )
U10HL074225 ( U.S. NIH Grant/Contract )
U10HL074227 ( U.S. NIH Grant/Contract )
U10HL074231 ( U.S. NIH Grant/Contract )
Y02 HL51810
First Submitted: October 27, 1999
First Posted: October 28, 1999
Last Update Posted: January 16, 2017
Last Verified: August 2006

Additional relevant MeSH terms:
Lung Diseases
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases
Adrenergic Agents
Adrenergic beta-Agonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Bronchodilator Agents
Autonomic Agents
Peripheral Nervous System Agents
Anti-Asthmatic Agents
Respiratory System Agents
Tocolytic Agents
Reproductive Control Agents
Adrenergic beta-2 Receptor Agonists
Adrenergic Agonists
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Gout Suppressants
Antirheumatic Agents
Tubulin Modulators