Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) (WAFACS)
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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00000541 |
Recruitment Status :
Completed
First Posted : October 28, 1999
Last Update Posted : July 15, 2020
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Cardiovascular Diseases Coronary Arteriosclerosis Coronary Disease Heart Diseases Myocardial Infarction Myocardial Ischemia | Behavioral: dietary supplements Drug: vitamin C Drug: vitamin E Drug: beta-carotene Drug: folic acid/Vitamin B6/Vitamin B12 | Phase 2 |
Study Type : | Interventional (Clinical Trial) |
Allocation: | Randomized |
Intervention Model: | Factorial Assignment |
Primary Purpose: | Prevention |
Official Title: | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) |
Study Start Date : | May 1993 |
Actual Primary Completion Date : | July 2005 |
Actual Study Completion Date : | July 2005 |

- Cardiovascular disease
- Cancer

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Ages Eligible for Study: | 40 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000541
OverallOfficial: | JoAnn Manson | Brigham and Women's Hospital |
Other Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | JoAnn E. Manson, MD, Chief, Division of Preventive Medicine, Brigham and Women's Hospital; Professor of Medicine and the Michael and Lee Bell Professor of Women's Health, Harvard Medical School, Brigham and Women's Hospital |
ClinicalTrials.gov Identifier: | NCT00000541 |
Other Study ID Numbers: |
84 R01HL046959 ( U.S. NIH Grant/Contract ) |
First Posted: | October 28, 1999 Key Record Dates |
Last Update Posted: | July 15, 2020 |
Last Verified: | July 2020 |
Cardiovascular Diseases Myocardial Infarction Heart Diseases Coronary Disease Coronary Artery Disease Myocardial Ischemia Arteriosclerosis Infarction Ischemia Pathologic Processes Necrosis Vascular Diseases Arterial Occlusive Diseases Vitamins Folic Acid |
Vitamin E Vitamin B 12 Hydroxocobalamin Vitamin B 6 Pyridoxal Pyridoxine Beta Carotene Vitamin B Complex Carotenoids Micronutrients Physiological Effects of Drugs Antioxidants Molecular Mechanisms of Pharmacological Action Protective Agents Hematinics |