Treatment of Hypertension
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|ClinicalTrials.gov Identifier: NCT00000484|
Recruitment Status : Completed
First Posted : October 28, 1999
Last Update Posted : November 26, 2013
|Condition or disease||Intervention/treatment||Phase|
|Cardiovascular Diseases Heart Diseases Hypertension Vascular Diseases||Drug: chlorothiazide Drug: Rauwolfia alkaloids||Phase 3|
This grant-supported, cooperative, fixed-protocol clinical study was initiated in 1966 and followed a cooperative study of the treatment of renal hypertension initiated in 1960 to evaluate the relative efficacy of several recognized drug regimens for reduction of blood pressure. Six centers (USPHS hospitals) and a coordinating center were involved in the trial.
Randomized, double-blind, fixed sample. Three hundred and eighty nine eligible patients were assigned to drug therapy consisting of chlorothiazide plus Rauwolfia serpentina or to placebo.
The study completion date listed in this record was inferred from last publication listed in the Citations section of this study record.
|Study Type :||Interventional (Clinical Trial)|
|Study Start Date :||April 1966|
|Actual Study Completion Date :||January 1979|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000484
|OverallOfficial:||Anthony Damato||USPHS Hospital|
|OverallOfficial:||Richard Thurm||USPHS Hospital|
|OverallOfficial:||Christfried Urner||USPHS Hospital|
|OverallOfficial:||John Vaillancourt||USPHS Hospital|
|OverallOfficial:||J. Warbasse||USPHS Hospital|
|OverallOfficial:||Robert Wells||USPHS Hospital|