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Bypass Angioplasty Revascularization Investigation (BARI)

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ClinicalTrials.gov Identifier: NCT00000462
Recruitment Status : Completed
First Posted : October 28, 1999
Last Update Posted : May 13, 2016
Information provided by:
National Heart, Lung, and Blood Institute (NHLBI)

Brief Summary:
To assess the relative long-term safety and efficacy of percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass graft (CABG) surgery in patients with multivessel disease and severe angina or ischemia who required revascularization and had coronary anatomy suitable for either procedure.

Condition or disease Intervention/treatment Phase
Angina Pectoris Cardiovascular Diseases Coronary Disease Diabetes Mellitus Heart Diseases Myocardial Ischemia Procedure: angioplasty, transluminal, percutaneous coronary Procedure: coronary artery bypass Phase 3

  Show Detailed Description

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
Study Start Date : April 1987
Estimated Study Completion Date : November 2004

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Angioplasty
U.S. FDA Resources

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Multivessel coronary artery disease requiring revascularization and suitable for either PTCA or CABG.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000462

Sponsors and Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
OverallOfficial: Katherine Detre University of Pittsburgh

BARI Investigators: Protocol for the Bypass Angioplasty Revascularization Investigation. Supplement to Circulation, 84:6, 1991.
Rosen AD: A SAS Interface to System 1032: Writing a user-maintainable interface to data management systems. Proc of Seventeenth Annual SAS Users Group International Conference, Cary, NC, SAS Institute Inc. pp 313, 1992.
Alderman E, Stadius M: The angiographic definitions of the Bypass Angioplasty Revascularization Investigation. Current Science, 3:1189-1207, 1992.
Letters to the Editor: Bypass Angioplasty Revascularization Investigation. N Engl J Med, 336:136-138, 1997.
Frye RL, King SB III, Sopko G, et al (Eds): A Symposium: Multivessel PTCA Versus CABG: Baseline Data from the Bypass Angioplasty Revascularization Investigation (BARI) and the Emory Angioplasty Surgery Trial (EAST). Am J Cardiol, 75: 1C-59C, 1995.

ClinicalTrials.gov Identifier: NCT00000462     History of Changes
Other Study ID Numbers: 51
U01HL038610 ( U.S. NIH Grant/Contract )
First Posted: October 28, 1999    Key Record Dates
Last Update Posted: May 13, 2016
Last Verified: March 2005

Additional relevant MeSH terms:
Diabetes Mellitus
Cardiovascular Diseases
Heart Diseases
Coronary Disease
Coronary Artery Disease
Myocardial Ischemia
Angina Pectoris
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Pathologic Processes
Vascular Diseases
Arterial Occlusive Diseases
Chest Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms